Metabonomics: a developing platform for better understanding Chinese herbal teas as a complementary therapy. (21st July 2016)

• Record Type: Journal Article
• Authors: You, Rong; Guan, Yanqing; Li, Lin
• Is Part Of: International journal of food science & technology. Volume 52:Number 1(2017)
• Page Start: 13
• Page End: 21
• Publication Date: 2016-07-21
• Subjects: Chinese herbal teas -- complementary therapy -- metabonomics -- molecular mechanisms; Food industry and trade -- Periodicals; 664
• DOI: 10.1111/ijfs.13206
• Languages: English
• ISSNs: 0950-5423

Abstract

Summary: Chinese herbal teas (CHTs) have gained increasing attention throughout the world as a complementary therapy. Due to the multicomponent composition in herbal teas, the molecular mechanisms of their causality in health effects are still elusive and becoming the main obstacles for their application. There is a pressing need for a more systematic study about their molecular mechanisms to substantiate the health effects of CHTs. With the particular feature of measuring the real metabolic phenotype resulted from molecular interplay between host and environmental factors, metabonomics is especially suited to inspect metabolic responses to CHT intake and provide insights into health effects. Application of metabonomics to uncover the effects of CHTs on human health is foreseen as providing deeper insights of the complicated molecular mechanisms of CHTs by explaining relatively subtle and different effects of herbal tea intervention, classifying the metabolic responses to herbal tea, depicting synergistic effects of CHTs and evaluating the safety of CHTs intake. Abstract : The general outline of metabonomics application in uncovering the molecular mechanism of CHTs effects on human health.