Anti‐acetylcholinesterase, antidiabetic, anti‐inflammatory, antityrosinase and antixanthine oxidase activities of Moroccan propolis. (21st June 2016)

• Record Type: Journal Article
• Authors: El‐Guendouz, Soukaina; Aazza, Smail; Lyoussi, Badiaâ; Antunes, Maria D.; Faleiro, Maria L.; Miguel, Maria G.
• Is Part Of: International journal of food science & technology. Volume 51:Number 8(2016)
• Page Start: 1762
• Page End: 1773
• Publication Date: 2016-06-21
• Subjects: α‐amylase -- α‐glucosidase -- hyaluronidase -- hydroethanolic extracts -- lipoxygenase -- propolis; Food industry and trade -- Periodicals; 664
• DOI: 10.1111/ijfs.13133
• Languages: English
• ISSNs: 0950-5423

Abstract

Summary: Biological properties of Moroccan propolis have been scarcely studied. In the present work, the total phenols and flavonoids from 21 samples of propolis collected in different places of Morocco or 3 supplied in the market were determined, as well as the in vitro capacity for inhibiting the activities of acetylcholinesterase, α‐glucosidase, α‐amylase, lipoxygenase, tyrosinase, xanthine oxidase and hyaluronidase. The results showed that samples 1 (region Fez‐Boulemane, Sefrou city) (IC50 = 0.065, 0.006, 0.020, 0.050, 0.014 mg mL −1 ) and 23 (marketed) (IC50 = 0.018, 0.002, 0.046, 0.037, 0.008 mg mL −1 ) had the best in vitro capacity for inhibiting the α‐amylase, α‐glucosidase, lipoxygenase, tyrosinase and xanthine oxidase activities, respectively. A negative correlation between IC50 values and concentration of phenols, flavones and flavanones was found. These activities corresponded to the generally higher amounts of phenols and flavonoids. In the same region, propolis samples have dissimilar phenol content and enzyme inhibitory activities. Abstract : Capacity of extracts of propolis from diverse places of morocco for inhibiting acetylcholinesterase, tyrosinase, α‐amylase, α‐glucosidase, lipoxygenase, hyaluronidase and xanthine‐oxidase.