A simple aptamer-functionalized gold nanorods based biosensor for the sensitive detection of MCF-7 breast cancer cells. Issue 20 (16th February 2016)

• Record Type: Journal Article
• Authors: Li, Yuan; Zhang, Yulong; Zhao, Man; Zhou, Qianqian; Wang, Lili; Wang, Huizhong; Wang, Xiaohui; Zhan, Linsheng
• Is Part Of: Chemical communications. Volume 52:Issue 20(2016)
• Page Start: 3959
• Page End: 3961
• Publication Date: 2016-02-16
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c6cc01014h
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Herein, we describe a novel approach for the rapid diagnosis of human breast carcinoma MCF-7 cells with a detection limit of 100 cells mL −1 . Abstract : Herein, we describe a novel approach for the rapid diagnosis of human breast carcinoma MCF-7 cells with a detection limit of 100 cells mL −1 . In our strategy, the MCF-7 cells are specially recognized by mucin 1 protein (MUC-1) aptamer-functionalized gold nanorods (GNRs) through specific interactions, whose signals are simply read out by its unique localized surface plasmon resonance (LSPR) spectra.