A simple aptamer-functionalized gold nanorods based biosensor for the sensitive detection of MCF-7 breast cancer cells. Issue 20 (16th February 2016) - Li, Yuan
Abstract : Herein, we describe a novel approach for the rapid diagnosis of human breast carcinoma MCF-7 cells with a detection limit of 100 cells mL −1 . Abstract : Herein, we describe a novel approach for the rapid diagnosis of human breast carcinoma MCF-7 cells with a detection limit of 100 cells mL −1 . In our strategy, the MCF-7 cells are specially recognized by mucin 1 protein (MUC-1) aptamer-functionalized gold nanorods (GNRs) through specific interactions, whose signals are simply read out by its unique localized surface plasmon resonance (LSPR) spectra.