Unusual C19-diterpenoid alkaloids from Aconitum vilmorinianum var. patentipilum. (December 2015)

• Record Type: Journal Article
• Authors: Cai, Le; Fang, Hai-xian; Yin, Tian-peng; Yu, Jing; Li, Zhen-jie; Dong, Jian-wei; Ding, Zhong-tao
• Is Part Of: Phytochemistry letters. Volume 14(2015:Dec.)
• Page Start: 106
• Page End: 110
• Publication Date: 2015-12
• Subjects: Aconitum vilmorinianum var. patentipilum -- Ranunculaceae -- Diterpenoid alkaloid -- Vilmotenitine; Botanical chemistry -- Periodicals; Chimie végétale -- Périodiques; 572.205
• DOI: 10.1016/j.phytol.2015.09.010
• Languages: English
• ISSNs: 1874-3900

Abstract

Graphical abstract: Highlights: Ten diterpenoid alkaloids were isolated from A . vilmorinianum var. patentipilum . Vilmotenitines A (1 ) and B (2 ) possess a unique rearranged six-membered B ring. Vilmotenitines C (3 ) possesses a keto group rarely placed at C-1. Abstract: Three new C19 -diterpenoid alkaloids vilmotenitines A-C (1 -3 ), together with seven known ones, vilmorine D (4 ), talatizidine (5 ), isotalatizidine (6 ), vilmorrianine B (7 ), vilmorrianine D (8 ), talatizamine (9 ), 8-deacetyl-yunaconitine (10 ), were isolated from Aconitum vilmorinianum var. patentipilum . Vilmotenitines A (1 ) and B (2 ) are the second natural occurrences of C19 -diterpenoid alkaloids with a unique rearranged six-membered B ring formed by the C(8) –C(10) linkage.