Unusual C19-diterpenoid alkaloids from Aconitum vilmorinianum var. patentipilum. (December 2015) - Cai, Le
Graphical abstract: Highlights: Ten diterpenoid alkaloids were isolated from A . vilmorinianum var. patentipilum . Vilmotenitines A (1 ) and B (2 ) possess a unique rearranged six-membered B ring. Vilmotenitines C (3 ) possesses a keto group rarely placed at C-1. Abstract: Three new C19 -diterpenoid alkaloids vilmotenitines A-C (1 -3 ), together with seven known ones, vilmorine D (4 ), talatizidine (5 ), isotalatizidine (6 ), vilmorrianine B (7 ), vilmorrianine D (8 ), talatizamine (9 ), 8-deacetyl-yunaconitine (10 ), were isolated from Aconitum vilmorinianum var. patentipilum . Vilmotenitines A (1 ) and B (2 ) are the second natural occurrences of C19 -diterpenoid alkaloids with a unique rearranged six-membered B ring formed by the C(8) –C(10) linkage.