Defective cytokine production early after multiple traumas: Modulation in severe sepsis. Issue 2 (December 2015)

• Record Type: Journal Article
• Authors: Paraschos, Michael D.; Patrani, Maria; Pistiki, Aikaterini; Katsenos, Chrysostomos; Tsaganos, Thomas; Netea, Mihai G.; Giamarellos-Bourboulis, Evangelos J.; Mandragos, Konstantinos
• Is Part Of: Cytokine. Volume 76:Issue 2(2015)
• Page Start: 222
• Page End: 226
• Publication Date: 2015-12
• Subjects: Cytokines -- Periodicals; 571.844
• DOI: 10.1016/j.cyto.2015.05.021
• Languages: English
• ISSNs: 1043-4666

Abstract

<abstract xml:lang="en" abstract-type="author-highlights" id="ab005"> <title id="st005">Highlights</title> <sec> <p id="sp0005"> <list id="l0005"> <list-item id="o0005"> <label></label> <p id="p0005">There is a significant down-regulation of innate immune responses after severe injury.</p> </list-item> <list-item id="o0010"> <label></label> <p id="p0010">Over-production of interferon-gamma is linked with trauma-related multiple organ failure.</p> </list-item> <list-item id="o0015"> <label></label> <p id="p0015">Transition to severe sepsis is accompanied by over-production of tumour necrosis factor-alpha.</p> </list-item> </list> </p> </sec> </abstract>