Identification of 3′-hydroxygenistein as a potent melanogenesis inhibitor from biotransformation of genistein by recombinant Pichia pastoris. Issue 10 (October 2015)

• Record Type: Journal Article
• Authors: Ding, Hsiou-Yu; Chiang, Chien-Min; Tzeng, Wei-Ming; Chang, Te-Sheng
• Is Part Of: Process biochemistry. Volume 50:Issue 10(2015:Oct.)
• Page Start: 1614
• Page End: 1617
• Publication Date: 2015-10
• Subjects: Biochemical engineering -- Periodicals; Biotechnology -- Periodicals; Biochemistry -- periodicals; Biotechnology -- periodicals; Chemical Engineering -- periodicals; Génie biochimique -- Périodiques; Biotechnologie -- Périodiques; Biochemical engineering; Biotechnology; Periodicals; 660.63
• DOI: 10.1016/j.procbio.2015.06.007
• Languages: English
• ISSNs: 1359-5113

Abstract

<abstract abstract-type="graphical" id="abs0005"> <title id="sect0005">Graphical abstract</title> <fig id="fig0030" position="anchor"> <graphic position="anchor" xlink:href="ark:/27927/pgj2h3ngt1g" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /> </fig> <sec> <p id="spar0005">A recombinant <italic>Pichia pastoris</italic> catalyzed biotransformation of genistein into 3′-hydroxygenistein, which was confirmed as a potent tyrosinase inhibitor and inhibited melanogenesis in B16 cells.</p> </sec> </abstract>