Highly sensitive turn-on biosensors by regulating fluorescent dye assembly on liposome surfaces1. Issue 50 (25th June 2015)

• Record Type: Journal Article
• Authors: Seo, Sungbaek; Kwon, Min Sang; Phillips, Andrew W.; Seo, Deokwon; Kim, Jinsang
• Is Part Of: Chemical communications. Volume 51:Issue 50(2015)
• Page Start: 10229
• Page End: 10232
• Publication Date: 2015-06-25
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c5cc01621e
• Languages: English
• ISSNs: 1359-7345

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgj1zk58spn" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />Herein, we developed a turn-on type liposome-based sensing platform by assembling fluorescence dyes to form H-type aggregation with emission quenching on phospholipid-liposome surfaces. Rationally devised specific interactions between the phospholipid and a target analyte effectively release the fluorescence dyes from H-aggregate, producing a turn-on signal.</p> </abstract>