Highly sensitive turn-on biosensors by regulating fluorescent dye assembly on liposome surfaces1. Issue 50 (25th June 2015) - Seo, Sungbaek
Abstract Herein, we developed a turn-on type liposome-based sensing platform by assembling fluorescence dyes to form H-type aggregation with emission quenching on phospholipid-liposome surfaces. Rationally devised specific interactions between the phospholipid and a target analyte effectively release the fluorescence dyes from H-aggregate, producing a turn-on signal.