The potential protective role of the combination of IL-22 and TNF-α against genital tract Chlamydia trachomatis infection. Issue 1 (May 2015)

• Record Type: Journal Article
• Authors: Zhao, Xiumin; Zhu, Danyang; Ye, Jiangbin; Li, Xingqun; Wang, Zhibin; Zhang, Lifang; Xu, Wen
• Is Part Of: Cytokine. Volume 73:Issue 1(2015)
• Page Start: 66
• Page End: 73
• Publication Date: 2015-05
• Subjects: Cytokines -- Periodicals; 571.844
• DOI: 10.1016/j.cyto.2015.01.027
• Languages: English
• ISSNs: 1043-4666

Abstract

<abstract xml:lang="en" abstract-type="author-highlights" id="ab005"> <title id="st110">Highlights</title> <sec> <p id="sp0005"> <list id="l0005"> <list-item id="o0005"> <label></label> <p id="p0165">MOECs expressed murine β-defensin 2 and the antimicrobial chemokines CXCL-9, -10, and -11.</p> </list-item> <list-item id="o0010"> <label></label> <p id="p0170">MOECs treated with IL-22 and TNF-α or a Th22 cell supernatant could recruit Th1 cells.</p> </list-item> <list-item id="o0015"> <label></label> <p id="p0175">MOECs treated with IL-22 and TNF-α or a Th22 cell supernatant could inhibit <italic>Chlamydia trachomatis</italic> growth.</p> </list-item> <list-item id="o0020"> <label></label> <p id="p0180">IL-22 and TNF-α or a Th22 cell supernatant exert a positive role in controlling genital epithelial damage.</p> </list-item> </list> </p> </sec> </abstract>