The potential protective role of the combination of IL-22 and TNF-α against genital tract Chlamydia trachomatis infection. Issue 1 (May 2015) - Zhao, Xiumin
Highlights MOECs expressed murine β-defensin 2 and the antimicrobial chemokines CXCL-9, -10, and -11. MOECs treated with IL-22 and TNF-α or a Th22 cell supernatant could recruit Th1 cells. MOECs treated with IL-22 and TNF-α or a Th22 cell supernatant could inhibit Chlamydia trachomatis growth. IL-22 and TNF-α or a Th22 cell supernatant exert a positive role in controlling genital epithelial damage.