Expression of membrane complement regulators, CD46, CD55 and CD59, in mesothelial cells of patients on peritoneal dialysis therapy. Issue 2 (June 2015)

• Record Type: Journal Article
• Authors: Sei, Yumi; Mizuno, Masashi; Suzuki, Yasuhiro; Imai, Masaki; Higashide, Keiko; Harris, Claire L.; Sakata, Fumiko; Iguchi, Daiki; Fujiwara, Michitaka; Kodera, Yasuhiro; Maruyama, Shoichi; Matsuo, Seiichi; Ito, Yasuhiko
• Is Part Of: Molecular immunology. Volume 65:Issue 2(2015:Jun.)
• Page Start: 302
• Page End: 309
• Publication Date: 2015-06
• Subjects: Immunochemistry -- Periodicals; Molecular biology -- Periodicals; Immunochemistry -- Periodicals; Allergy and Immunology -- Periodicals; Molecular Biology -- Periodicals; Immunochimie -- Périodiques; Biologie moléculaire -- Périodiques; Immunochemistry; Molecular biology; Periodicals; Electronic journals; 571.96
• DOI: 10.1016/j.molimm.2015.02.005
• Languages: English
• ISSNs: 0161-5890

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0085"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">Membrane complement regulators abundantly express in peritoneal mesothelial cells.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">Mesothelial expression of CD55 was related to sC5b-9 level in peritoneal dialysate.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Decrease of CD55 expression might enhance complement activation in mesothelial cells.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">Peritoneal dialysis therapy may modify expression of CD55 in peritoneum.</p> </list-item> <list-item id="lsti0025"> <label></label> <p id="par0025">Expression of CD55 in mesothelium may be a surrogate marker of peritoneal function.</p> </list-item> </list> </p> </sec> </abstract>