Expression of membrane complement regulators, CD46, CD55 and CD59, in mesothelial cells of patients on peritoneal dialysis therapy. Issue 2 (June 2015) - Sei, Yumi
Highlights Membrane complement regulators abundantly express in peritoneal mesothelial cells. Mesothelial expression of CD55 was related to sC5b-9 level in peritoneal dialysate. Decrease of CD55 expression might enhance complement activation in mesothelial cells. Peritoneal dialysis therapy may modify expression of CD55 in peritoneum. Expression of CD55 in mesothelium may be a surrogate marker of peritoneal function.