The effect of Cu2+ on arginine kinase from Euphausia superba: A computational simulation integrating unfolding and aggregation studies. Issue 3 (March 2015)

• Record Type: Journal Article
• Authors: Cheng, Juan-Ge; Si, Yue-Xiu; Lee, Jinhyuk; Zhao, Feng; Yang, Jun-Mo; Qian, Guo-Ying; Yin, Shang-Jun; Park, Yong-Doo
• Is Part Of: Process biochemistry. Volume 50:Issue 3(2015:Mar.)
• Page Start: 395
• Page End: 405
• Publication Date: 2015-03
• Subjects: Biochemical engineering -- Periodicals; Biotechnology -- Periodicals; Biochemistry -- periodicals; Biotechnology -- periodicals; Chemical Engineering -- periodicals; Génie biochimique -- Périodiques; Biotechnologie -- Périodiques; Biochemical engineering; Biotechnology; Periodicals; 660.63
• DOI: 10.1016/j.procbio.2014.12.010
• Languages: English
• ISSNs: 1359-5113

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">Arginine kinase from <italic>E. superb</italic> (ESAK) inactivation mechanisms by Cu²⁺ ligand binding.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">Kinetic analysis of Cu²⁺-induced ESAK aggregation.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Several osmolytes roles for preventing ESAK aggregation and recovering activity.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">Computational molecular dynamics simulation between ESAK and Cu²⁺.</p> </list-item> </list> </p> </sec> </abstract>