New molecular targets in non clear renal cell carcinoma: An overview of ongoing clinical trials. Issue 7 (July 2015)

• Record Type: Journal Article
• Authors: Ciccarese, Chiara; Massari, Francesco; Santoni, Matteo; Heng, Daniel Y.C.; Sotte, Valeria; Brunelli, Matteo; Conti, Alessandro; Cheng, Liang; Lopez-Beltran, Antonio; Scarpelli, Marina; Cascinu, Stefano; Tortora, Giampaolo; Montironi, Rodolfo
• Is Part Of: Cancer treatment reviews. Volume 41:Issue 7(2015)
• Page Start: 614
• Page End: 622
• Publication Date: 2015-07
• Subjects: Cancer -- Periodicals; Cancer -- Treatment -- Periodicals; Neoplasms -- therapy -- Periodicals; Cancer -- Périodiques; Cancer -- Traitement -- Périodiques; Cancer -- Treatment; Electronic journals; Periodicals; 616.99406
• DOI: 10.1016/j.ctrv.2015.05.006
• Languages: English
• ISSNs: 0305-7372

Abstract

<abstract xml:lang="en" abstract-type="author-highlights" id="ab005"> <title> <x xml:space="preserve">Abstract</x> </title> <sec> <title id="st005">Highlights</title> <p id="sp0005"> <list id="l0020"> <list-item id="o0130"> <label></label> <p id="p0130">nccRCC subtypes differ for their biological and clinical behavior.</p> </list-item> <list-item id="o0135"> <label></label> <p id="p0135">VEGF/VEGFR, mTOR and MET signaling pathways play a prominent role in nccRCC.</p> </list-item> <list-item id="o0140"> <label></label> <p id="p0140">The efficacy of anti PD-1/PDL-1 approaches should be tested in nccRCC patients.</p> </list-item> <list-item id="o0145"> <label></label> <p id="p0145">Understanding the molecular landscape of nccRCC is crucial for future therapies.</p> </list-item> </list> </p> </sec> </abstract>