New molecular targets in non clear renal cell carcinoma: An overview of ongoing clinical trials. Issue 7 (July 2015) - Ciccarese, Chiara
Abstract Highlights nccRCC subtypes differ for their biological and clinical behavior. VEGF/VEGFR, mTOR and MET signaling pathways play a prominent role in nccRCC. The efficacy of anti PD-1/PDL-1 approaches should be tested in nccRCC patients. Understanding the molecular landscape of nccRCC is crucial for future therapies.