Systems biology in 3D space – enter the morphome. Issue 2 (February 2015)

• Record Type: Journal Article
• Authors: Lucocq, John M.; Mayhew, Terry M.; Schwab, Yannick; Steyer, Anna M.; Hacker, Christian
• Is Part Of: Trends in cell biology. Volume 25:Issue 2(2015)
• Page Start: 59
• Page End: 64
• Publication Date: 2015-02
• Subjects: Cytology -- Periodicals; Cytology -- Research -- Periodicals; 571.6
• DOI: 10.1016/j.tcb.2014.09.008
• Languages: English
• ISSNs: 0962-8924

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">We define the morphome as the distribution of matter in a 3D object.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">Morphomics methods characterize or quantify 3D data at ground truth level.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Stereology is the most efficient and precise archetypal morphomics method.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">Stereology can be applied to solve the big data problem in serial EM.</p> </list-item> <list-item id="lsti0025"> <label></label> <p id="par0025">Stereology can be applied to make quantitative links between nanoscale imaging modes.</p> </list-item> </list> </p> </sec> </abstract>