Systems biology in 3D space – enter the morphome. Issue 2 (February 2015) - Lucocq, John M.
Highlights We define the morphome as the distribution of matter in a 3D object. Morphomics methods characterize or quantify 3D data at ground truth level. Stereology is the most efficient and precise archetypal morphomics method. Stereology can be applied to solve the big data problem in serial EM. Stereology can be applied to make quantitative links between nanoscale imaging modes.