Genetic engineering to improve 1, 3-propanediol production in an isolated Citrobacter freundii strain. Issue 1 (January 2015)

• Record Type: Journal Article
• Authors: Celińska, Ewelina; Drożdżyńska, Agnieszka; Jankowska, Marta; Białas, Wojciech; Czaczyk, Katarzyna; Grajek, Włodzimierz
• Is Part Of: Process biochemistry. Volume 50:Issue 1(2015:Jan.)
• Page Start: 48
• Page End: 60
• Publication Date: 2015-01
• Subjects: Biochemical engineering -- Periodicals; Biotechnology -- Periodicals; Biochemistry -- periodicals; Biotechnology -- periodicals; Chemical Engineering -- periodicals; Génie biochimique -- Périodiques; Biotechnologie -- Périodiques; Biochemical engineering; Biotechnology; Periodicals; 660.63
• DOI: 10.1016/j.procbio.2014.09.001
• Languages: English
• ISSNs: 1359-5113

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005"> <italic>Citrobacter freundii</italic> strain was genetically modified for improved 1, 3-PD production.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">Overexpression of PDOR activity in a custom made vector was carried out.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Accumulation of toxic 3-HPA was decreased in the modified strain.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">The modified strain produced more 1, 3-PD in flask and bioreactor cultures.</p> </list-item> </list> </p> </sec> </abstract>