Lithium inhibits palatal fusion and osteogenic differentiation in palatal shelves in vitro. Issue 3 (March 2015)

• Record Type: Journal Article
• Authors: Meng, Liuyan; Wang, Xinhuan; Torensma, Ruurd; Von den Hoff, Johannes W.; Bian, Zhuan
• Is Part Of: Archives of oral biology. Volume 60:Issue 3(2015:Mar.)
• Page Start: 501
• Page End: 507
• Publication Date: 2015-03
• Subjects: Mouth -- Periodicals; Mouth -- Diseases -- Periodicals; Dentistry -- Periodicals; Electronic journals; 617.6005
• DOI: 10.1016/j.archoralbio.2014.12.011
• Languages: English
• ISSNs: 0003-9969

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">LiCl induces persistence of the midline epithelial seam (MES) and causes failure of palatal fusion.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">LiCl prevents osteogenic differentiation in palatal shelves.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">LiCl may activate the canonical Wnt signaling to impair the fusion of the secondary palate.</p> </list-item> </list> </p> </sec> </abstract>