Phytochemical screening, anticancer and antioxidant activities of Origanum vulgare L. ssp. viride (Boiss.) Hayek, a plant of traditional usage. (16th October 2014)

• Record Type: Journal Article
• Authors: Koldaş, Serkan; Demirtas, Ibrahim; Ozen, Tevfik; Demirci, Mehmet Ali; Behçet, Lütfi
• Is Part Of: Journal of the science of food and agriculture. Volume 95:Number 4(2015:Mar. 15)
• Page Start: 786
• Page End: 798
• Publication Date: 2014-10-16
• Subjects: Food -- Periodicals; Agriculture -- Periodicals; 664
• DOI: 10.1002/jsfa.6903
• Languages: English
• ISSNs: 0022-5142

Abstract

<abstract abstract-type="main" id="jsfa6903-abs-0001"> <title>Abstract</title> <sec id="jsfa6903-sec-0001" sec-type="section"> <title>BACKGROUND</title> <p id="jsfa6903-para-0001">A detailed phytochemical analysis of <italic>Origanum vulgare</italic> L. ssp. <italic>viride</italic> (Boiss.) Hayek was carried out and the antioxidant activities of five different crude extracts were determined. The antiproliferative activities of the extracts were determined using the xCELLigence system (Real Time Cell Analyzer).</p> </sec> <sec id="jsfa6903-sec-0002" sec-type="section"> <title>RESULTS</title> <p id="jsfa6903-para-0002">Differences between the essential oil and volatile organic compound profiles of the plant were shown. The main component of the essential oil was caryophyllene oxide, while the main volatile organic compounds were sabinene and eucalyptol as determined by HS‐GC/MS. Phenolic contents of the extracts were determined qualitatively and quantitatively by HPLC/TOF‐MS. Ten phenolic compounds were found in the extracts from <italic>O. vulgare</italic> and <italic>Origanum acutidens</italic>: rosmarinic acid (in highest abundance), chicoric acid, caffeic acid, <italic>p</italic>‐coumaric acid, gallic acid, quercetin, apigenin‐7‐glucoside, kaempferol, naringenin and 4‐hydroxybenzaldehyde.</p> </sec> <sec id="jsfa6903-sec-0003" sec-type="section"> <title>CONCLUSION</title> <p id="jsfa6903-para-0003">This study provides first results on the antiproliferative and antioxidant properties and detailed phytochemical screening of <italic>O. vulgare</italic> ssp. <italic>viride</italic> (Boiss.) Hayek. © 2014 Society of Chemical Industry</p> </sec> </abstract>