Chemical composition, antioxidant, antimicrobial and cytotoxic activities of Tagetes minuta and Ocimum basilicum essential oils. Issue 2 (16th January 2014)

• Record Type: Journal Article
• Authors: Shirazi, Mohsen Taheri; Gholami, Hamid; Kavoosi, Gholamreza; Rowshan, Vahid; Tafsiry, Asad
• Is Part Of: Food science & nutrition. Volume 2:Issue 2(2014:Mar.)
• Page Start: 146
• Page End: 155
• Publication Date: 2014-01-16
• Subjects: Food industry and trade -- Periodicals; Food -- Periodicals; Nutrition -- Periodicals; 664
• DOI: 10.1002/fsn3.85
• Languages: English
• ISSNs: 2048-7177

Abstract

<abstract abstract-type="main" id="fsn385-abs-0001"> <title>Abstract</title> <p>Chemical composition, antioxidant, antimicrobial and cytotoxic activities of <italic>Tagetes minuta</italic> (TM) essential oil (TMO) and <italic>Ocimum basilicum</italic> (OB) essential oil (OBO) were examined. The main components for TMO were dihydrotagetone (33.9%), E‐ocimene (19.9%), tagetone (16.1%), <italic>cis</italic>‐<italic>β</italic>‐ocimene (7.9%), Z‐ocimene (5.3%), limonene (3.1%) and epoxyocimene (2.03%). The main components for OBO were methylchavicol (46.9%), geranial (19.1%), neral (15.15%), geraniol (3.0%), nerol (3.0%), caryophyllene (2.4%). Inhibitory concentrations (IC<sub>50</sub>) for reactive oxygen species (ROS) and reactive nitrogen species (RNS) scavenging were 12–17 and 200–250 <italic>μ</italic>g/mL of TMO and OBO, respectively. Minimal inhibitory concentration (MIC) against <italic>Salmonella typhi</italic>, <italic> Escherichia coli</italic>, <italic> Staphylococcus aureus</italic>, <italic> Bacillus subtilis</italic>, <italic> Aspergillus niger</italic>, and <italic>Candida albicans</italic> were 150 ± 8, 165 ± 9, 67 ± 8, 75 ± 7, 135 ± 15, and 115 ± 8 <italic>μ</italic>g/mL of TMO, respectively. MIC for <italic>S. typhi</italic>, <italic> E. coli</italic>, <italic> S. aureus</italic>, <italic> B. subtilis</italic>, <italic> A. niger</italic>, and <italic>C. albicans</italic> were 145 ± 8, 160 ± 7, 45 ± 4, 40 ± 3, 80 ± 9, and 95 ± 7 <italic>μ</italic>g/mL of OBO, respectively. IC<sub>50</sub> for nasopharyngeal cancer cell line (KB) and liver hepatocellular carcinoma cell line (HepG2) were 75 ± 5 and 70 ± 4 <italic>μ</italic>g/mL of TMO, respectively. IC<sub>50</sub> for KB and HepG2 were 45 ± 4 and 40 ± 3 <italic>μ</italic>g/mL of OBO, respectively. Thus, they could be used as an effective source of natural antioxidant and antibacterial additive to protect foods from oxidative damages and foodborne pathogens. Furthermore, they could be promising candidate for antitumor drug design.</p> </abstract>