Beneficial Effects of Black Yeast Derived 1-3, 1-6 Beta Glucan-Nichi Glucan in a Dyslipidemic Individual of Indian Origin—A Case Report. (1st March 2014)

• Record Type: Journal Article
• Authors: Ganesh, Jegatheesan Saravana; Rao, Yegneswara Yellury; Ravikumar, Ratnagiri; Jayakrishnan, Gosalakkal A.; Iwasaki, Masaru; Preethy, Senthilkumar; Abraham, Samuel JK
• Is Part Of: Journal of dietary supplements. Volume 11:Number 1(2014:Mar.)
• Page Start: 1
• Page End: 6
• Publication Date: 2014-03-01
• Subjects: Dietary supplements -- Periodicals; Dietary Supplements -- Periodicals; 613.205
• DOI: 10.3109/19390211.2013.859211
• Languages: English
• ISSNs: 1939-0211

Abstract

<abstract> <title>ABSTRACT</title> <p>Dyslipidemia is a major risk factor for the development of cardiovascular diseases and statins are the common drugs used to correct dyslipidemia. Herein, we report a case where the subject was a nondiabetic, dyslipidemia patient on medication with Rosuvastatin. After the intake of Rosuvastatin, his triglycerides decreased to a minimum of 220 mg/dL. In order to augment the action of Rosuvastatin, he was advised to take 1.5 mg of Nichi Glucan food supplement, which is a 1, 3-1, 6 Beta Glucan derived from the black yeast, <italic>Aureobasidium pullulans, </italic> daily for 2 months. At the end of 2 months, his triglyceride levels decreased from 523 mg/dL (at start of the study) to 175 mg/dL. His VLDL levels, which were 104.6 mg/dL at the start of the study decreased to 35 mg/dL and the HDL cholesterol levels increased from 27 to 38 mg/dL. This is a first of its kind report on the effect of the black yeast derived 1, 3-1, 6 Beta Glucans on dyslipidemia not associated with diabetes. Thus supplementation of Nichi Glucan, 1, 3- 1, 6 Beta Glucan derived from the black yeast along with the routine medications was beneficial to treat dyslipidemia and a larger trial is needed to confirm the effects.</p> </abstract>