Cancer genetics and therapeutics focus on phytochemicals /: focus on phytochemicals. (2019)

• Record Type: Book
• Further Information: Note: Madhumita Roy, Amitava Datta.
• Other Names: Roy, Madhumita; (Computer scientist), Datta, Amitava
• Contents: Intro; Foreword; Preface; Contents; About the Authors; 1 Cancer: Types and Hallmarks; 1.1 What Is Cancer?; 1.1.1 Types of Cancer; 1.1.1.1 Carcinoma; 1.1.1.2 Sarcoma; 1.1.1.3 Leukemia; 1.1.1.4 Lymphoma; 1.1.1.5 Myeloma; 1.1.1.6 Melanoma; 1.1.1.7 Brain and Spinal Cord Tumors; 1.2 Hallmarks of Cancer; 1.2.1 Sustaining Proliferative Signaling; 1.2.2 Evading Growth Suppressors; 1.2.2.1 Disruption of Contact Inhibition; 1.2.3 Resisting Cell Death; 1.2.4 Enabling Replicative Immortality; 1.2.5 Inducing Angiogenesis; 1.2.6 Activating Invasion and Metastasis; 1.2.7 Reprogramming Energy Metabolism 1.2.8 Evading Immune Destruction1.2.9 Genetic Instability and Mutation; 1.2.10 Tumor-Promoting Inflammation; 1.3 Cancer Diagnosis and Treatment; 1.3.1 Risk Factors and Causes of Cancer; 1.3.2 Symptoms; 1.3.3 Diagnosis; 1.3.3.1 Biopsy; 1.3.3.2 Imaging; 1.3.4 Treatment; 1.4 Conclusion; References; 2 Cancer: Genetics and Important Pathways; 2.1 Introduction; 2.2 Degree of Gene Mutations in Tumorigenesis; 2.3 Driver and Passenger Mutations; 2.4 Cancer-Specific Genomic Landscapes; 2.4.1 Genomic Landscape of Breast Cancer; 2.4.1.1 Summary; 2.5 Genomic Landscape of Other Cancers 3.5 Classification of Phytochemicals3.5.1 Phenolics; 3.5.1.1 Phenolic Acids; 3.5.1.2 Tannins; 3.5.1.3 Stilbenes; 3.5.1.4 Coumarins; 3.5.2 Flavonoids; 3.5.3 Carotenoid; 3.5.4 Alkaloid; 3.5.5 Nitrogen-Containing Compounds; 3.5.6 Organosulfur Compounds; 3.5.7 Benefits of Dietary Phytochemicals; 3.6 Conclusion; References; 4 Drugs and Phytochemicals; 4.1 Introduction; 4.2 Classification of Chemotherapy Drugs; 4.2.1 Alkylating Agents; 4.2.2 Antimetabolites; 4.2.3 Antitumor Antibiotics; 4.2.4 Topoisomerase Inhibitors; 4.2.5 Mitotic Inhibitors; 4.2.6 Corticosteroids 4.3 Mode of Action of Chemotherapeutic Drugs4.4 Benefits of Plant-Derived Medicines; 4.5 Plant-Derived Anticancer Drugs; 4.6 Other Phytochemicals as Anticancer Agents; 4.7 Conclusion; References; 5 Molecular Mechanisms of Phytochemical Actions in Cancer; 5.1 Introduction; 5.2 Epigenetic Control; 5.2.1 Histone Modification; 5.2.2 DNA Methylation; 5.2.3 miRNAs; 5.3 Keap1-Nrf2 Pathway; 5.4 Oxidative Stress; 5.5 Inflammation; 5.6 Roles of Dietary Phytochemicals in Oxidative Stress; 5.6.1 Phytochemicals and Oxidative Stress; 5.6.1.1 Phenolic Phytochemicals and Oxidative Stress
• Publisher Details: Singapore : Springer
• Publication Date: 2019
• Extent: 1 online resource (239 p.)
• Subjects: 616.99/4042; Cancer -- Genetic aspects; Cancer -- Treatment; Cancer -- Prevention; Phytochemicals; Cancer -- Genetic aspects; Cancer -- Prevention; Cancer -- Treatment; Phytochemicals; Electronic books; Electronic books
• Languages: English
• ISBNs: 9789811394713; 9811394717
• Related ISBNs: 9789811394706
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.