Microbiome and metabolome in diagnosis, therapy, and other strategic applications. ([2019])

• Record Type: Book
• Further Information: Note: [edited by] Joel Faintuch, Salomao Faintuch.
• Editors: Faintuch, Joel; Faintuch, Salomão
• Contents: Front Cover; Microbiome and Metabolome in Diagnosis, Therapy, and other Strategic Applications; Microbiome and Metabolome in Diagnosis, Therapy, and other Strategic Applications; Copyright; Contents; Contributors; Introduction to the Microbiome and Metabolome; HISTORY; SCIENTIFIC APPROACHES; THE BIRTH OF CURRENT MICROBIOME STUDIES; THE METABOLOME AND OTHER; THE ERA OF MULTIOMICS; REFERENCES; Useful Internet Sites; I -- Tools, Toolstations and Models; 1 -- Germ-Free Animals as a Tool to Study Indigenous Microbiota; INTRODUCTION; OBTAINING AND MAINTAINING GERM-FREE ANIMALS; Purpose of Use Germ-Free AnimalsGnotobiotic Animals; Gnotobiotic Animals With Simplified Microbial Consortia; Germ-Free Animals With Transplanted Eubiotic or Dysbiotic Microbiota From the Same or Other Animal Species; Conventionalized or Conventional Animals; CONCLUSION; REFERENCES; 2 -- Germ-Free Mouse Technology in Cardiovascular Research; THE VARIOUS WAYS TO STUDY HOST-MICROBIAL INTERACTIONS; A Short History of Germ-Free Research; Some Thoughts and Concerns on the Present Status of Germ-Free Research; THE COMMENSAL IMPACT ON THE MATURATION AND VIGILANCE OF IMMUNITY; Adaption of Lymphoid Tissues Influence of the Microbiota Versus Germ-free or Antibiotic TreatmentMicrobiota-Derived Metabolite Trimethylamine-N-Oxide; Trimethylamine-N-Oxide and Human Disease; Implications of the Microbiota in Thrombosis; Endothelial Platelet Deposition; Vascular Events in Inflammatory Bowel Disease; PERSPECTIVE; LIST OF ACRONYMS AND ABBREVIATIONS; REFERENCES; 3 -- The Gut Microbiome Beyond the Bacteriome-The Neglected Role of Virome and Mycobiome in Health and Disease; GENERAL FEATURES OF THE GUT MICROBIOME; CORE GUT VIROME AND ITS PHYSIOLOGIC IMPORTANCE; Inflammatory Responses Actions of the Gut Virome on the Host GenomeCORE GUT MYCOBIOME AND ITS PHYSIOLOGIC ROLE; Lifestyle and the Mycobiome; Systemic Impact; Fungal Virulence; Yeast-to-Hyphae Transition; ROLES IN DISEASE STATES; Virus Latent State; Commensal Fungi and Progression of Infectious Diseases; Fungal Signature in Obesity and Inflammatory Bowel Disease; Virome-Mycobiome Interactions; Prophage-Bacteria-Host Synergy; FUTURE ASPECTS OF THE MANIPULATION OF GUT VIROME AND GUT MYCOBIOME; REFERENCES; 4 -- Techniques for Phenotyping the Gut Microbiota Metabolome; METABOLOMICS IN THE CONTEXT OF SYSTEMS BIOLOGY
• Publisher Details: London, United Kingdom : Academic Press
• Publication Date: 2019
• Extent: 1 online resource
• Subjects: 572/.472; Microorganisms; Bacteria; Microorganisms -- Therapeutic use; Bacteria -- Therapeutic use; Medical microbiology; Probiotics; SCIENCE / Life Sciences / Biochemistry; Electronic books
• Languages: English
• ISBNs: 9780128152508; 0128152508
• Related ISBNs: 9780128152492
• Notes: Note: Includes bibliographical references and index.; Note: Online resource; title from PDF title page (EBSCO, viewed January 10, 2019).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.