Chemical analysis of non-antimicrobial veterinary drug residues in food. (2016)

• Record Type: Book
• Further Information: Note: Edited by Jack F. Kay, James D. MacNeil, Jian Wang.
• Editors: Kay, Jack F; MacNeil, James D; Wang, Jian, 1964-
• Contents: Preface List of contributors About the Editors Chapter 1: Basic Considerations for the Analyst for Veterinary Drug Residues Analysis in Animal Tissues; James D. MacNeil and Jack F. Kay 1.1 Introduction 1.2 Pharmacokinetics 1.3 Metabolism and Distribution 1.4 Choice of Analytical Method 1.5 Importance of Regulatory Limits 1.6 International Obligations for Regulatory Analytical Laboratories 1.7 Conclusions References Chapter 2: Emerging Techniques in Sample Extraction and Rapid Analysis; Wendy C. Andersen, Sherri B. Turnipseed, and Jack J. Lohne 2.1 Introduction 2.2. Sample Extraction 2.3. Extract Clean-Up with Solid Phase Sorbents 2.4. Micro Extraction Techniques for Solvent and Sorbent Extraction 2.5 Emerging Techniques in Liquid Chromatography 2.6 Direct Mass Spectrometry Analysis of Sample Extracts 2.7 Ion Mobility Spectrometry 2.8 Conclusions References Chapter 3: Capabilities and Limitations of High Resolution Mass Spectrometry (HRMS): Time of Flight and Orbitrap™; Anton Kaufmann and Phil Teale 3.1 Available Technology 3.2 Capabilities and Limitations of the Technology as Compared to LC-MS/MS (Tandem Quadrupole Mass Spectrometer) 3.3 Analytical Methods for Veterinary Drug Residues 3.4 Doping Control 3.5 Accurate Mass MS in Research and Metabolism Studies 3.6 Designer Drugs and Generic Detection Strategies 3.7 The Future of Accurate Mass Spectrometry in Residue Analysis Chapter 4: Hormones and β-Agonists; Leendert A. van Ginkel, Toine Bovee, Marco H. Blokland, Saskia S, Sterk, Nathalie G.E. Smits, Jelka Pleadin and Ana Vulić 4.1 Introduction 4.2 Advances in Classical Analysis of Exogenous Synthetic Hormones 4.3 Bio-based Screening Methods for Steroid Hormones, β-Agonists and Growth Hormones 4.4 Natural Hormones 4.5 Control for Synthetic β-agonists: Screening and Confirmatory Methods References Chapter 5: Analysis of Anthelmintic and Anticoccidial Drug Residues in Animal-Derived Foods; Sarah Tuck, Ambrose Furey and Martin Danaher 5.1 Introduction 5.2 Chemistry and Mode of Action 5.3 Legislation 5.4 Sample Preparation Protocols for Antiparasitic Agents in Food Matrices 5.5 LC-MS and GC-MS Detection of Antiparasitic Agents in Food 5.6 Conclusions References Chapter 6: Sedatives and Tranquilizers; Vesna Cerkvenik Flajs and James D. MacNeil 6.1 Introduction 6.2 Classification and Representative Compounds 6.3 Use of Sedatives and Tranquilizers to Prevent Stress Syndrome During the Transport of Pigs to Slaughter 6.4 Sedatives and Tranquilizers with an Approved Veterinary Use in Food-producing Animals 6.5 Sedatives and Tranquilizers without an Approved Veterinary Use in Food-producing Animals 6.6 Cocktails 6.7 Issues of Environmental Contamination 6.8 Maximum Residue Limits (MRLs) 6.9 Systematic Veterinary Control over Residues and Surveillance Studies 6.10 Analyte Stability 6.11 Analytical Methods for Determination of Residues 6.12 Performance and Validation of the Analytical Methods References Chapter 7: The Use of Pyrethroids, Carbamates, Organophosphates and Other Pesticides in Veterinary Medicine; Christine Akre 7.1 Introduction 7.2 Veterinary Drug Properties, Structures and Regulation 7.3 Toxicology, Pharmacokinetics and Metabolism 7.4 Analytical Methods 7.5 Conclusion References Chapter 8: Non-steroidal Anti-inflammatory Drugs; Joe O. Boison, Fernando J. Ramos and Alan Chicoine 8.1. Introduction: What are Pain Killers (Analgesics) and NSAIDs? 8.2. Veterinary Drug Properties, Structures, and Regulation 8.3. Pharmacokinetics/Metabolism 8.4 Acceptable Daily Intake (ADI) 8.5. Maximum Residue Limits/Tolerances 8.6. Analysis of NSAID Residues in Food 8.7. Literature Reviews of Analytical Methods for NSAIDs in Biological Samples 8.8 New Developments in NSAIDs 8.9. Conclusion References Chapter 9: Certain Dyes as Pharmacologically Active Substances in Fish Farming and other Aquaculture Products; Eric Verdon and Wendy C. Andersen 9.1 Introduction 9.2 Therapeutic Applications and Chemistry of Certain Dyes used in Fish Farming 9.3 Toxicological Issues 9.4 Regulatory Issues 9.5 Analytical Methods for Residue Control 9.6. Recent Trading Issues with Dye Alerts 9.7 Conclusions References Chapter 10: Method Validation and QA/QC Approaches for Multi-residue Methods; Andrew Cannavan, Jack F. Kay and Zora Jandrić 10.1 Introduction 10.2 Sources of Guidance on Method Validation 10.3 Practical Considerations 10.4 Examples of Validation Protocols for MRMs 10.5 Quality Assurance / Quality Control 10.6 Conclusion References INDEX
• Edition: 1st
• Publisher Details: Hoboken, New Jersey : John Wiley & Sons, Inc
• Publication Date: 2016
• Extent: 1 online resource
• Subjects: 664.07; Veterinary drug residues; Food contamination
• Languages: English
• ISBNs: 9781119325901; 9781119325918
• Related ISBNs: 9781118695074
• Notes: Note: Description based on CIP data; item not viewed.
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