1. An iminium ion metabolite hampers the production of the pharmacologically active metabolite of a multikinase inhibitor KW‐2449 in primates: irreversible inhibition of aldehyde oxidase and covalent binding with endogenous proteins. (13th March 2018) Authors: Hosogi, Jun; Ohashi, Rui; Maeda, Hiroshi; Fujita, Kazuhiro; Ushiki, Junko; Kuwabara, Takashi; Yamamoto, Yorihiro; Imamura, Toru Journal: Biopharmaceutics & drug disposition Issue: Volume 39:Number 3(2018:Apr.) Page Start: 164 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Ascorbic acid and CoQ10 ameliorate the reproductive ability of superoxide dismutase 1-deficient female mice. Issue 1 (2nd August 2019) Authors: Ishii, Naoki; Homma, Takujiro; Lee, Jaeyong; Mitsuhashi, Hikaru; Yamada, Ken-ichi; Kimura, Naoko; Yamamoto, Yorihiro; Fujii, and Junichi Journal: Biology of reproduction Issue: Volume 102:Issue 1(2020) Page Start: 102 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. Edaravone, a potent free radical scavenger, reacts with peroxynitrite to produce predominantly 4-NO-edaravone. (3rd May 2016) Authors: Fujisawa, Akio; Yamamoto, Yorihiro Journal: Redox report Issue: Volume 21:Number 3(2016) Page Start: 98 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
4. Endogenous reactive oxygen species cause astrocyte defects and neuronal dysfunctions in the hippocampus: a new model for aging brain. Issue 1 (13th September 2016) Authors: Ishii, Takamasa; Takanashi, Yumi; Sugita, Koichi; Miyazawa, Masaki; Yanagihara, Rintaro; Yasuda, Kayo; Onouchi, Hiromi; Kawabe, Noboru; Nakata, Munehiro; Yamamoto, Yorihiro; Hartman, Phil S.; Ishii, Naoaki Journal: Aging cell Issue: Volume 16:Issue 1(2017) Page Start: 39 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
5. Hypothermia does not hasten death during uncontrolled hemorrhagic shock presenting as the "triad of death" in rats. Issue 1 (21st August 2014) Authors: Nishi, Kouichirou; Takasu, Akira; Shinozaki, Hirotoshi; Sakamoto, Ken; Yamamoto, Yorihiro; Sakamoto, Toshihisa Journal: Acute medicine & surgery Issue: Volume 2:Issue 1 (2015) Page Start: 29 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
6. Increased oxidative stress in patients with amyotrophic lateral sclerosis and the effect of edaravone administration. (3rd May 2016) Authors: Nagase, Midori; Yamamoto, Yorihiro; Miyazaki, Yusuke; Yoshino, Hiide Journal: Redox report Issue: Volume 21:Number 3(2016) Page Start: 104 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
7. Monoamine oxidase B oxidizes a novel multikinase inhibitor KW-2449 to its iminium ion and aldehyde oxidase further converts it to the oxo-piperazine form in human. Issue 5 (October 2017) Authors: Hosogi, Jun; Ohashi, Rui; Maeda, Hiroshi; Tashiro, Satoshi; Fuse, Eiichi; Yamamoto, Yorihiro; Kuwabara, Takashi Journal: Drug metabolism and pharmacokinetics Issue: Volume 32:Issue 5(2017) Page Start: 255 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
8. Observed adducts on positive mode direct analysis in real time mass spectrometry – Proton/ammonium adduct selectivities of 600-sample in-house chemical library. Issue 1 (February 2017) Authors: Sugimura, Natsuhiko; Furuya, Asami; Yatsu, Takahiro; Igarashi, Yoko; Aoyama, Reiko; Izutani, Chisato; Yamamoto, Yorihiro; Shibue, Toshimichi Journal: European journal of mass spectrometry Issue: Volume 23:Issue 1(2017) Page Start: 4 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
9. PB-08 SEM analysis of long-term coenzyme Q10 deficient cell model. (21st November 2019) Authors: Tanaka, Tsukika; Sato, Michio; Okamoto, Mizuho; Nakamura, Akari; Fujisawa, Akio; Yamamoto, Yorihiro; Kashiba, Misato Journal: Microscopy Issue: Volume 68(2019)Supplement 1 Page Start: i49 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
10. Randomized, double-blind, placebo-controlled pilot trial of reduced coenzyme Q10 for Parkinson's disease. Issue 8 (August 2015) Authors: Yoritaka, Asako; Kawajiri, Sumihiro; Yamamoto, Yorihiro; Nakahara, Toshiki; Ando, Maya; Hashimoto, Kazuhiko; Nagase, Midori; Saito, Yufuko; Hattori, Nobutaka Journal: Parkinsonism & related disorders Issue: Volume 21:Issue 8(2015) Page Start: 911 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗