1. A multicenter, phase I, pharmacokinetic study of osimertinib in cancer patients with normal renal function or severe renal impairment. Issue 4 (22nd June 2020) Authors: Vishwanathan, Karthick; Sanchez‐Simon, Inmaculada; Keam, Bhumsuk; Penel, Nicolas; de Miguel‐Luken, Maria; Weilert, Doris; Mills, Andrew; Marotti, Marcelo; Johnson, Martin; Ravaud, Alain Journal: Pharmacology research & perspectives Issue: Volume 8:Issue 4(2020) Page Start: n/a Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. A PET study in healthy subjects of brain exposure of 11C-labelled osimertinib – A drug intended for treatment of brain metastases in non-small cell lung cancer. Issue 4 (April 2020) Authors: Varrone, Andrea; Varnäs, Katarina; Jucaite, Aurelija; Cselényi, Zsolt; Johnström, Peter; Schou, Magnus; Vazquez-Romero, Ana; Moein, Mohammad M; Halldin, Christer; Brown, Andrew P; Vishwanathan, Karthick; Farde, Lars Journal: Journal of cerebral blood flow & metabolism Issue: Volume 40:Issue 4(2020) Page Start: 799 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. A Phase 1 Study to Evaluate Absolute Bioavailability and Absorption, Distribution, Metabolism, and Excretion of Savolitinib in Healthy Male Volunteers. Issue 4 (19th February 2023) Authors: Miah, Kowser; Vishwanathan, Karthick; Scarfe, Graeme; Li, Yan; Hara, Indira; Cantarini, Mireille; Argue, John; Menakuru, Somasekhar R. Journal: Clinical pharmacology in drug development Issue: Volume 12:Issue 4(2023) Page Start: 424 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
4. Absolute Bioavailability of Osimertinib in Healthy Adults. Issue 2 (23rd April 2018) Authors: Vishwanathan, Karthick; So, Karen; Thomas, Karen; Bramley, Alex; English, Stephen; Collier, Jo Journal: Clinical pharmacology in drug development Issue: Volume 8:Issue 2(2019) Page Start: 198 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
5. Absorption, distribution, metabolism and elimination of 14C-ETX0914, a novel inhibitor of bacterial type-II topoisomerases in rodents. (2nd January 2017) Authors: Guo, Jian; Joubran, Camil; Luzietti, Ricardo A.; Basarab, Gregory S.; Grimm, Scott W.; Vishwanathan, Karthick Journal: Xenobiotica Issue: Volume 47:Number 1(2017) Page Start: 31 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
6. Acalabrutinib CYP3A‐mediated drug–drug interactions: Clinical evaluations and physiologically based pharmacokinetic modelling to inform dose adjustment strategy. Issue 8 (28th March 2022) Authors: Chen, Buyun; Zhou, Diansong; Wei, Hua; Yotvat, Marmor; Zhou, Li; Cheung, Jean; Sarvaria, Nicole; Lai, Richard; Sharma, Shringi; Vishwanathan, Karthick; Ware, Joseph Journal: British journal of clinical pharmacology Issue: Volume 88:Issue 8(2022) Page Start: 3716 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
7. Clinical evaluation of the potential drug–drug interactions of savolitinib: Interaction with rifampicin, itraconazole, famotidine or midazolam. Issue 2 (21st August 2021) Authors: Ren, Song; Vishwanathan, Karthick; Cantarini, Mireille; Frewer, Paul; Hara, Indira; Scarfe, Graeme; Burke, Wendy; Schalkwijk, Stein; Li, Yan; Han, David; Goldwater, Ronald Journal: British journal of clinical pharmacology Issue: Volume 88:Issue 2(2022) Page Start: 655 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
8. CTNI-09. A PHASE I HEALTHY VOLUNTEER STUDY ON THE RELATIVE BIOAVAILABILITY AND FOOD EFFECT OF CAPSULE AND GRANULE FORMULATIONS OF SELUMETINIB. (9th November 2020) Authors: Cohen-Rabbie, Sarit; Mattinson, Alexandra; So, Karen; Wang, Nan; McBride, Eileen; Vishwanathan, Karthick; Goldwater, Ronald Journal: Neuro-oncology Issue: Volume 22(2020)Supplement 2 Page Start: ii43 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
9. Development, Verification, and Prediction of Osimertinib Drug–Drug Interactions Using PBPK Modeling Approach to Inform Drug Label. (15th March 2018) Authors: Pilla Reddy, Venkatesh; Walker, Michael; Sharma, Pradeep; Ballard, Peter; Vishwanathan, Karthick Journal: CPT: pharmacometrics & systems pharmacology Issue: Volume 7:Number 5(2018) Page Start: 321 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
10. Effect of multiple‐dose osimertinib on the pharmacokinetics of simvastatin and rosuvastatin. (10th October 2018) Authors: Harvey, R. Donald; Aransay, Noemi Reguart; Isambert, Nicolas; Lee, Jong‐Seok; Arkenau, Tobias; Vansteenkiste, Johan; Dickinson, Paul A.; Bui, Khanh; Weilert, Doris; So, Karen; Thomas, Karen; Vishwanathan, Karthick Journal: British journal of clinical pharmacology Issue: Volume 84:Number 12(2018) Page Start: 2877 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗