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Author/Creator Sweeney, Zachary K.

1. A brain penetrant progranulin biotherapeutic rescues lysosomal and inflammatory phenotypes in the brain of GRN knockout mice: Lipids in AD and FTD: From genes to interventions. (7th December 2020)

Authors:
Logan, Todd; DeVos, Sarah; Simon, Matthew J.; Davis, Sonnet; Wang, Junhua; Low, Ray; Huang, Fen; Rajendra, Yashas; Prorok, Rachel; Sun, Elizabeth; Rana, Anil; Hsiao‐Nakamoto, Jennifer; Mosesova, Sofia; Zhu, Yuda; Cherf, Gerald M.; Lengerich, Bettina; Bhalla, Akhil; Kim, Do Jin; Chan, Darren; Duqu...
Journal:
Alzheimer's & dementia
Issue:
Volume 16(2020)Supplement 2
Page Start:
n/a
Record Type:
Journal Article
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2. Development of a cyclosporin A derivative with excellent anti-hepatitis C virus potency. Issue 4 (15th February 2018)

Authors:
Fu, Jiping; Becker, Christopher; Cao, Li; Capparelli, Michael; Denay, Regis; Fujimoto, Roger; Gai, Yu; Gao, Zhaobo; Guenat, Christian; Karur, Subramanian; Kim, Hongyong; Li, Weikuan; Li, Xiaolin; Li, Wei; Lochmann, Thomas; Lu, Amy; Lu, Peichao; Luneau, Alexandre; Meier, Nicole; Mergo, Wosenu
Journal:
Bioorganic & medicinal chemistry
Issue:
Volume 26:Issue 4(2018)
Page Start:
957
Record Type:
Journal Article
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3. Discovery of potent azaindazole leucine-rich repeat kinase 2 (LRRK2) inhibitors possessing a key intramolecular hydrogen bond – Part 2. Issue 4 (15th February 2019)

Authors:
Shore, Daniel G.M.; Sweeney, Zachary K.; Beresford, Alan; Chan, Bryan K.; Chen, Huifen; Drummond, Jason; Gill, Andrew; Kleinheinz, Tracy; Liu, Xingrong; Medhurst, Andrew D.; McIver, Edward G.; Moffat, John G.; Zhu, Haitao; Estrada, Anthony A.
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 29:Issue 4(2019)
Page Start:
674
Record Type:
Journal Article
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4. Finding the perfect spot for fluorine: Improving potency up to 40-fold during a rational fluorine scan of a Bruton's Tyrosine Kinase (BTK) inhibitor scaffold. Issue 2 (15th January 2015)

Authors:
Lou, Yan; Sweeney, Zachary K.; Kuglstatter, Andreas; Davis, Dana; Goldstein, David M.; Han, Xiaochun; Hong, Junbae; Kocer, Buelent; Kondru, Rama K.; Litman, Renee; McIntosh, Joel; Sarma, Keshab; Suh, Judy; Taygerly, Joshua; Owens, Timothy D.
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 25:Issue 2(2015)
Page Start:
367
Record Type:
Journal Article
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Available online (eLD content is only available in our Reading Rooms) ↗

5. Finding the perfect spot for fluorine: Improving potency up to 40-fold during a rational fluorine scan of a Bruton's Tyrosine Kinase (BTK) inhibitor scaffold. Issue 2 (15th January 2015)

Authors:
Lou, Yan; Sweeney, Zachary K.; Kuglstatter, Andreas; Davis, Dana; Goldstein, David M.; Han, Xiaochun; Hong, Junbae; Kocer, Buelent; Kondru, Rama K.; Litman, Renee; McIntosh, Joel; Sarma, Keshab; Suh, Judy; Taygerly, Joshua; Owens, Timothy D.
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 25:Issue 2(2015)
Page Start:
367
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗