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Author/Creator Steffgen, Jürgen

1. 32 Safety, pharmacokinetics and pharmacodynamics of BI 705564, a covalent inhibitor of brutons tyrosine kinase in phase 1 clinical trials in healthy volunteers. (April 2019)

Authors:
Litzenburger, Tobias; Müller, Fabian; Schultz, Armin; Klein, Elliott; Ramanujam, Meera; Wu, Jing; Wiebe, Sabrina; Benediktus, Ewald; Hui, Jianan; Li, Xiujiang; Flack, Mary; Padula, Steven J; Visvanathan, Sudha; Steffgen, Jürgen; Hünnemeyer, Andreas
Journal:
Lupus science & medicine
Issue:
Volume 6(2019)supplement 1
Page Start:
A23
Record Type:
Journal Article
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2. Effects of BI 655064, an antagonistic anti-CD40 antibody, on clinical and biomarker variables in patients with active rheumatoid arthritis: a randomised, double-blind, placebo-controlled, phase IIa study. Issue 6 (22nd June 2019)

Authors:
Visvanathan, Sudha; Daniluk, Stefan; Ptaszyński, Rafał; Müller-Ladner, Ulf; Ramanujam, Meera; Rosenstock, Bernd; Eleftheraki, Anastasia G; Vinisko, Richard; Petříková, Alena; Kellner, Herbert; Dokoupilova, Eva; Kwiatkowska, Brygida; Alten, Rieke; Schwabe, Christian; Baum, Patrick; Joseph, David; ...
Journal:
Annals of the rheumatic diseases
Issue:
Volume 78:Issue 6(2019)
Page Start:
754
Record Type:
Journal Article
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3. Effects of BI 655064, an antagonistic anti-CD40 antibody, on clinical and biomarker variables in patients with active rheumatoid arthritis: a randomised, double-blind, placebo-controlled, phase IIa study. Issue 6 (22nd March 2019)

Authors:
Visvanathan, Sudha; Daniluk, Stefan; Ptaszyński, Rafał; Müller-Ladner, Ulf; Ramanujam, Meera; Rosenstock, Bernd; Eleftheraki, Anastasia G; Vinisko, Richard; Petříková, Alena; Kellner, Herbert; Dokoupilova, Eva; Kwiatkowska, Brygida; Alten, Rieke; Schwabe, Christian; Baum, Patrick; Joseph, David; ...
Journal:
Annals of the rheumatic diseases
Issue:
Volume 78:Issue 6(2019)
Page Start:
754
Record Type:
Journal Article
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4. FC 049A RANDOMISED DOSE RANGING, PLACEBO-CONTROLLED, PHASE II STUDY ASSESSING THE EFFICACY AND SAFETY OF BI 655064, AN ANTAGONISTIC ANTI-CD40 ANTIBODY, IN PATIENTS WITH LUPUS NEPHRITIS. (29th May 2021)

Authors:
Jayne, David; Furie, Richard; Romero-Diaz, Juanita; Amano, Hirofumi; Noppakun, Kajohnsak; Gomez, Harold Michael; Recto, Rhona; Belsack, Valérie; Fagan, Nora; Padula, Steven; Revollo, Ivette; Wu, Jing; Visvanathan, Sudha; Steffgen, Jürgen
Journal:
Nephrology dialysis transplantation
Issue:
Volume 36(2021)Supplement 1
Page Start:
Record Type:
Journal Article
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5. Safety, pharmacokinetics and pharmacodynamics of BI 655064 in phase 1 clinical trials in healthy Chinese and Japanese subjects. Issue 4 (9th December 2020)

Authors:
Tsuda, Yasuhiro; Grimaldi, Christine; Huang, Fenglei; Benediktus, Ewald; Yagi, Nobutaka; Padula, Steven J.; Jang, In‐Jin; Steffgen, Jürgen
Journal:
British journal of clinical pharmacology
Issue:
Volume 87:Issue 4(2021)
Page Start:
2000
Record Type:
Journal Article
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6. Safety, pharmacokinetics and pharmacodynamics of BI 705564, a highly selective, covalent inhibitor of Bruton's tyrosine kinase, in Phase I clinical trials in healthy volunteers. Issue 4 (20th November 2020)

Authors:
Litzenburger, Tobias; Steffgen, Jürgen; Benediktus, Ewald; Müller, Fabian; Schultz, Armin; Klein, Elliott; Ramanujam, Meera; Harcken, Christian; Gupta, Alpana; Wu, Jing; Wiebe, Sabrina; Li, Xiujiang; Flack, Mary; Padula, Steven J.; Visvanathan, Sudha; Hünnemeyer, Andreas; Hui, Jianan
Journal:
British journal of clinical pharmacology
Issue:
Volume 87:Issue 4(2021)
Page Start:
1824
Record Type:
Journal Article
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7. Safety, Pharmacokinetics, and Pharmacodynamics of Multiple Rising Doses of BI 655064, an Antagonistic Anti‐CD40 Antibody, in Healthy Subjects: A Potential Novel Treatment for Autoimmune Diseases. (16th August 2018)

Authors:
Schwabe, Christian; Rosenstock, Bernd; Doan, Thi; Hamilton, Paul; Dunbar, P. Rod; Eleftheraki, Anastasia G.; Joseph, David; Hilbert, James; Schoelch, Corinna; Padula, Steven J.; Steffgen, Jürgen
Journal:
Journal of clinical pharmacology
Issue:
Volume 58:Number 12(2018)
Page Start:
1566
Record Type:
Journal Article
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