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Author/Creator Smith, Emery

2. Discovery and SAR of a novel series of potent, CNS penetrant M4 PAMs based on a non-enolizable ketone core: Challenges in disposition. Issue 17 (1st September 2016)

Authors:
Wood, Michael R.; Noetzel, Meredith J.; Tarr, James C.; Rodriguez, Alice L.; Lamsal, Atin; Chang, Sichen; Foster, Jarrett J.; Smith, Emery; Chase, Peter; Hodder, Peter S.; Engers, Darren W.; Niswender, Colleen M.; Brandon, Nicholas J.; Wood, Michael W.; Duggan, Mark E.; Conn, P. Jeffrey; Bridges,...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 26:Issue 17(2016)
Page Start:
4282
Record Type:
Journal Article
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3. High-Throughput Screening for Drugs That Inhibit Papain-Like Protease in SARS-CoV-2. (December 2020)

Authors:
Smith, Emery; Davis-Gardner, Meredith E.; Garcia-Ordonez, Ruben D.; Nguyen, Tu-Trinh; Hull, Mitchell; Chen, Emily; Baillargeon, Pierre; Scampavia, Louis; Strutzenberg, Timothy; Griffin, Patrick R.; Farzan, Michael; Spicer, Timothy P.
Journal:
SLAS discovery
Issue:
Volume 25:Number 10(2020)
Page Start:
1152
Record Type:
Journal Article
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5. Identification of Potential Pharmacoperones Capable of Rescuing the Functionality of Misfolded Vasopressin 2 Receptor Involved in Nephrogenic Diabetes Insipidus. (September 2016)

Authors:
Smith, Emery; Janovick, Jo Ann; Bannister, Thomas D.; Shumate, Justin; Scampavia, Louis; Conn, P. Michael; Spicer, Timothy P.
Journal:
Journal of biomolecular screening
Issue:
Volume 21:Number 8(2016)
Page Start:
824
Record Type:
Journal Article
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6. Discovery and optimization of a novel series of highly CNS penetrant M4 PAMs based on a 5, 6-dimethyl-4-(piperidin-1-yl)thieno[2, 3-d]pyrimidine core. Issue 13 (1st July 2016)

Authors:
Wood, Michael R.; Noetzel, Meredith J.; Engers, Julie L.; Bollinger, Katrina A.; Melancon, Bruce J.; Tarr, James C.; Han, Changho; West, Mary; Gregro, Alison R.; Lamsal, Atin; Chang, Sichen; Ajmera, Sonia; Smith, Emery; Chase, Peter; Hodder, Peter S.; Bubser, Michael; Jones, Carrie K.; Hopkins, C...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 26:Issue 13(2016)
Page Start:
3029
Record Type:
Journal Article
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7. Discovery and SAR of muscarinic receptor subtype 1 (M1) allosteric activators from a molecular libraries high throughput screen. Part 1: 2, 5-Dibenzyl-2H-pyrazolo[4, 3-c]quinolin-3(5H)-ones as positive allosteric modulators. Issue 2 (15th January 2015)

Authors:
Han, Changho; Chatterjee, Arindam; Noetzel, Meredith J.; Panarese, Joseph D.; Smith, Emery; Chase, Peter; Hodder, Peter; Niswender, Colleen; Conn, P. Jeffrey; Lindsley, Craig W.; Stauffer, Shaun R.
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 25:Issue 2(2015)
Page Start:
384
Record Type:
Journal Article
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8. Application of Parallel Multiparametric Cell-Based FLIPR Detection Assays for the Identification of Modulators of the Muscarinic Acetylcholine Receptor 4 (M4). (August 2015)

Authors:
Smith, Emery; Chase, Peter; Niswender, Colleen M.; Utley, Thomas J.; Sheffler, Douglas J.; Noetzel, Meredith J.; Lamsal, Atin; Wood, Michael R.; Conn, P. Jeffrey; Lindsley, Craig W.; Madoux, Franck; Acosta, Mary; Scampavia, Louis; Spicer, Timothy; Hodder, Peter
Journal:
Journal of biomolecular screening
Issue:
Volume 20:Number 7(2015)
Page Start:
858
Record Type:
Journal Article
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9. An Integrated Approach for Screening and Identification of Positive Allosteric Modulators of N-Methyl-D-Aspartate Receptors. (June 2016)

Authors:
Jambrina, Enrique; Cerne, Rok; Smith, Emery; Scampavia, Louis; Cuadrado, Maria; Findlay, Jeremy; Krambis, Michael J.; Wakulchik, Mark; Chase, Peter; Brunavs, Michael; Burris, Kevin D.; Gallagher, Peter; Spicer, Timothy P.; Ursu, Daniel
Journal:
Journal of biomolecular screening
Issue:
Volume 21:Number 5(2016)
Page Start:
468
Record Type:
Journal Article
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