1. A novel humanized mouse model of Huntington disease for preclinical development of therapeutics targeting mutant huntingtin alleles. (19th January 2017) Authors: Southwell, Amber L.; Skotte, Niels H.; Villanueva, Erika B.; Østergaard, Michael E.; Gu, Xiaofeng; Kordasiewicz, Holly B.; Kay, Chris; Cheung, Daphne; Xie, Yuanyun; Waltl, Sabine; Dal Cengio, Louisa; Findlay-Black, Hailey; Doty, Crystal N.; Petoukhov, Eugenia; Iworima, Diepiriye; Slama, Ramy; Ooi... Journal: Human molecular genetics Issue: Volume 26:Number 6(2017:Mar. 15) Page Start: 1115 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Asialoglycoprotein receptor 1 mediates productive uptake of N-acetylgalactosamine-conjugated and unconjugated phosphorothioate antisense oligonucleotides into liver hepatocytes. Issue 21 (23rd October 2017) Authors: Tanowitz, Michael; Hettrick, Lisa; Revenko, Alexey; Kinberger, Garth A.; Prakash, Thazha P.; Seth, Punit P. Journal: Nucleic acids research Issue: Volume 45:Issue 21(2017) Page Start: 12388 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. Identification of metabolically stable 5΄-phosphate analogs that support single-stranded siRNA activity. Issue 11 (1st May 2017) Authors: Prakash, Thazha P.; Lima, Walt F.; Murray, Heather M.; Li, Wenyu; Kinberger, Garth A.; Chappell, Alfred E.; Gaus, Hans; Seth, Punit P.; Bhat, Balkrishen; Crooke, Stanley T.; Swayze, Eric E. Journal: Nucleic acids research Issue: Volume 45:Issue 11(2017) Page Start: 6994 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗