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You searched for: Author/Creator Seth, Punit P.

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1. A convenient synthesis of 5′-triantennary N-acetyl-galactosamine clusters based on nitromethanetrispropionic acid. Issue 9 (1st May 2016)

2. A novel humanized mouse model of Huntington disease for preclinical development of therapeutics targeting mutant huntingtin alleles. (19th January 2017)

5. Conjugation of mono and di-GalNAc sugars enhances the potency of antisense oligonucleotides via ASGR mediated delivery to hepatocytes. Issue 15 (1st August 2016)

8. Disulfide bridge cross-linking between protein and the RNA backbone as a tool to study RNase H1. Issue 23 (1st December 2020)

9. Evaluation of the effect of 2′-O-methyl, fluoro hexitol, bicyclo and Morpholino nucleic acid modifications on potency of GalNAc conjugated antisense oligonucleotides in mice. Issue 23 (15th December 2018)

10. Identification of metabolically stable 5΄-phosphate analogs that support single-stranded siRNA activity. Issue 11 (1st May 2017)