1. Antibody-mediated delivery of chimeric protein degraders which target estrogen receptor alpha (ERα). Issue 4 (15th February 2020) Authors: Dragovich, Peter S.; Adhikari, Pragya; Blake, Robert A.; Blaquiere, Nicole; Chen, Jinhua; Cheng, Yun-Xing; den Besten, Willem; Han, Jinping; Hartman, Steven J.; He, Jintang; He, Mingtao; Rei Ingalla, Ellen; Kamath, Amrita V.; Kleinheinz, Tracy; Lai, Tommy; Leipold, Douglas D.; Li, Chun Sing; Liu,... Journal: Bioorganic & medicinal chemistry letters Issue: Volume 30:Issue 4(2020) Page Start: Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Conjugation of Indoles to Antibodies through a Novel Self‐Immolating Linker. Issue 19 (25th March 2018) Authors: Dragovich, Peter S.; Blake, Robert A.; Chen, Chunjiao; Chen, Jinhua; Chuh, Josefa; den Besten, Willem; Fan, Fang; Fourie, Aimee; Hartman, Steven J.; He, Changrong; He, Jintang; Ingalla, Ellen Rei; Kozak, Katherine R.; Leong, Steven R.; Lu, Jiawei; Ma, Yong; Meng, Lingyao; Nannini, Michelle; Oeh, ... Journal: Chemistry Issue: Volume 24:Issue 19(2018) Page Start: 4830 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. Discovery of GNE-502 as an orally bioavailable and potent degrader for estrogen receptor positive breast cancer. (15th October 2021) Authors: Zbieg, Jason R.; Liang, Jun; Li, Jun; Blake, Robert A.; Chang, Jae; Friedman, Lori; Goodacre, Simon; Hartman, Steven J.; Rei Ingalla, Ellen; Kiefer, James R.; Kleinheinz, Tracy; Labadie, Sharada; Lai, Tommy; Liao, Jiangpeng; McLean, Nev; Metcalfe, Ciara; Mody, Vidhi; Nannini, Michelle; Ortwine, D... Journal: Bioorganic & medicinal chemistry letters Issue: Volume 50(2021) Page Start: Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
4. Identification of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with no evidence of CYP3A4 time-dependent inhibition and improved aqueous solubility. Issue 3 (1st February 2015) Authors: Zak, Mark; Liederer, Bianca M.; Sampath, Deepak; Yuen, Po-wai; Bair, Kenneth W.; Baumeister, Timm; Buckmelter, Alexandre J.; Clodfelter, Karl H.; Cheng, Eric; Crocker, Lisa; Fu, Bang; Han, Bingsong; Li, Guangkun; Ho, Yen-Ching; Lin, Jian; Liu, Xiongcai; Ly, Justin; O'Brien, Thomas; Reynolds, Domi... Journal: Bioorganic & medicinal chemistry letters Issue: Volume 25:Issue 3(2015) Page Start: 529 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
5. Metabolic response of prostate cancer to nicotinamide phophoribosyltransferase inhibition in a hyperpolarized MR/PET compatible bioreactor. Issue 14 (14th July 2015) Authors: Keshari, Kayvan R.; Wilson, David M.; Van Criekinge, Mark; Sriram, Renuka; Koelsch, Bertram L.; Wang, Zhen J.; VanBrocklin, Henry F.; Peehl, Donna M.; O'Brien, Tom; Sampath, Deepak; Carano, Richard A. D.; Kurhanewicz, John Journal: Prostate Issue: Volume 75:Issue 14(2015) Page Start: 1601 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
6. Preclinical assessment of the ADME, efficacy and drug-drug interaction potential of a novel NAMPT inhibitor. (2nd September 2019) Authors: Liederer, Bianca M.; Cheong, Jonathan; Chou, Kang-Jye; Dragovich, Peter S.; Le, Hoa; Liang, Xiaorong; Ly, Justin; Mukadam, Sophie; Oeh, Jason; Sampath, Deepak; Wang, Leslie; Wong, Susan Journal: Xenobiotica Issue: Volume 49:Number 9(2019:Sep.) Page Start: 1063 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
7. Preclinical models of nicotinamide phosphoribosyltransferase inhibitor-mediated hematotoxicity and mitigation by co-treatment with nicotinic acid. (20th April 2015) Authors: Tarrant, Jacqueline M.; Dhawan, Preeti; Singh, Jatinder; Zabka, Tanja S.; Clarke, Emer; DosSantos, Garry; Dragovich, Peter S.; Sampath, Deepak; Lin, Tori; McCray, Bobbi; La, Nghi; Nguyen, Trung; Kauss, Ariel; Dambach, Donna; Misner, Dinah L.; Diaz, Dolores; Uppal, Hirdesh Journal: Toxicology mechanisms and methods Issue: Volume 25:Number 3(2015) Page Start: 201 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
8. Structure-based optimization of hydroxylactam as potent, cell-active inhibitors of lactate dehydrogenase. (1st March 2022) Authors: Wei, BinQing; Robarge, Kirk; Labadie, Sharada S.; Chen, Jinhua; Corson, Laura B.; DiPasquale, Antonio; Dragovich, Peter S.; Eigenbrot, Charles; Evangelista, Marie; Fauber, Benjamin P.; Hitz, Anna; Hong, Rebecca; Lai, Kwong Wah; Liu, Wenfeng; Ma, Shuguang; Malek, Shiva; O'Brien, Thomas; Pang, Jodi... Journal: Bioorganic & medicinal chemistry letters Issue: Volume 59(2022) Page Start: Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
9. Targeting MCL‐1 and BCL‐2 with polatuzumab vedotin and venetoclax overcomes treatment resistance in R/R non‐Hodgkin lymphoma: Results from preclinical models and a Phase Ib study. Issue 3 (17th January 2023) Authors: Lasater, Elisabeth A.; Amin, Dhara N.; Bannerji, Rajat; Mali, Raghuveer Singh; Barrett, Kathy; Rys, Ryan N.; Oeh, Jason; Lin, Eva; Sterne‐Weiler, Tim; Ingalla, Ellen Rei; Go, MaryAnn; Yu, Shang‐Fan; Krem, Maxwell M.; Arthur, Chris; Hahn, Uwe; Johnston, Anna; Karur, Vinit; Khan, Nadia; Marlton, Pa... Journal: American journal of hematology Issue: Volume 98:Issue 3(2023) Page Start: 449 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
10. Unexpected equivalent potency of a constrained chromene enantiomeric pair rationalized by co-crystal structures in complex with estrogen receptor alpha. Issue 7 (1st April 2019) Authors: Zhang, Birong; Kiefer, James R.; Blake, Robert A.; Chang, Jae H.; Hartman, Steven; Ingalla, Ellen Rei; Kleinheinz, Tracy; Mody, Vidhi; Nannini, Michelle; Ortwine, Daniel F.; Ran, Yingqing; Sambrone, Amy; Sampath, Deepak; Vinogradova, Maia; Zhong, Yu; Nwachukwu, Jerome C.; Nettles, Kendall W.; Lai... Journal: Bioorganic & medicinal chemistry letters Issue: Volume 29:Issue 7(2019) Page Start: 905 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗