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Author/Creator Sack, John S.

11. Discovery of potent and efficacious pyrrolopyridazines as dual JAK1/3 inhibitors. Issue 14 (15th July 2017)

Authors:
Hynes, John; Wu, Hong; Kempson, James; Duan, James J.-W.; Lu, Zhonghui; Jiang, Bin; Stachura, Sylwia; Tokarski, John S.; Sack, John S.; Khan, Javed A.; Lippy, Jonathan S.; Zhang, Rosemary F.; Pitt, Sidney; Shen, Guoxiang; Gillooly, Kate; McIntyre, Kim; Carter, Percy H.; Barrish, Joel C.; Nadler, ...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 27:Issue 14(2017)
Page Start:
3101
Record Type:
Journal Article
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12. Identification of bicyclic hexafluoroisopropyl alcohol sulfonamides as retinoic acid receptor-related orphan receptor gamma (RORγ/RORc) inverse agonists. Employing structure-based drug design to improve pregnane X receptor (PXR) selectivity. Issue 2 (15th January 2018)

Authors:
Gong, Hua; Weinstein, David S.; Lu, Zhonghui; Duan, James J.-W.; Stachura, Sylwia; Haque, Lauren; Karmakar, Ananta; Hemagiri, Hemalatha; Raut, Dhanya Kumar; Gupta, Arun Kumar; Khan, Javed; Camac, Dan; Sack, John S.; Pudzianowski, Andrew; Wu, Dauh-Rurng; Yarde, Melissa; Shen, Ding-Ren; Borowski, V...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 28:Issue 2(2018)
Page Start:
85
Record Type:
Journal Article
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13. Identification of potent, selective and orally bioavailable phenyl ((R)-3-phenylpyrrolidin-3-yl)sulfone analogues as RORγt inverse agonists. Issue 16 (15th August 2019)

Authors:
Lu, Zhonghui; Duan, James J.-W.; Xiao, Haiyun; Neels, James; Wu, Dauh-Rurng; Weigelt, Carolyn A.; Sack, John S.; Khan, Javed; Ruzanov, Max; An, Yongmi; Yarde, Melissa; Karmakar, Ananta; Vishwakrishnan, Sureshbabu; Baratam, Venkata; Shankarappa, Harisha; Vanteru, Sridhar; Babu, Venkatesh; Basha, M...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 29:Issue 16(2019)
Page Start:
2265
Record Type:
Journal Article
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14. Substituted benzyloxytricyclic compounds as retinoic acid-related orphan receptor gamma t (RORγt) agonists. Issue 12 (15th June 2020)

Authors:
Harikrishnan, Lalgudi S.; Gill, Patrice; Kamau, Muthoni G.; Qin, Lan-Ying; Ruan, Zheming; O'Malley, Daniel; Huynh, Tram; Stachura, Sylwia; Cavallaro, Cullen L.; Lu, Zhonghui; J.-W. Duan, James; Weigelt, Carolyn A.; Sack, John S.; Ruzanov, Max; Khan, Javed; Gururajan, Murali; Wong, Jessica J.; Hua...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 30:Issue 12(2020)
Page Start:
Record Type:
Journal Article
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15. Substituted diaryl ether compounds as retinoic acid-related orphan Receptor-γt (RORγt) agonists. (1st March 2021)

Authors:
Ruan, Zheming; Park, Peter K.; Wei, Donna; Purandare, Ashok; Wan, Honghe; O'Malley, Daniel; Stachura, Sylwia; Perez, Heidi; Cavallaro, Cullen L.; Weigelt, Carolyn A.; Sack, John S.; Ruzanov, Max; Khan, Javed; Gururajan, Murali; Wong, Jessica J.; Huang, Yanling; Yarde, Melissa; Li, Zhuyin; Chen, C...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 35(2021)
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Record Type:
Journal Article
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