1. A translational strategy employing physiologically based modelling to predict the pharmacological active dose of RO7119929, an oral prodrug of a targeted cancer immunotherapy TLR7 agonist. (3rd August 2022) Authors: Rynn, Caroline; Umehara, Kenichi; Jiang, Tianyi; Ait-Goughoulte, Malika; Parrott, Neil Journal: Xenobiotica Issue: Volume 52:Number 8(2022) Page Start: 855 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Application of a gut–liver-on-a-chip device and mechanistic modelling to the quantitative in vitro pharmacokinetic study of mycophenolate mofetil. Issue 15 (14th July 2022) Authors: Milani, Nicoló; Parrott, Neil; Ortiz Franyuti, Daniela; Godoy, Patricio; Galetin, Aleksandra; Gertz, Michael; Fowler, Stephen Journal: Lab on a chip Issue: Volume 22:Issue 15(2022) Page Start: 2853 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. Application of New Cellular and Microphysiological Systems to Drug Metabolism Optimization and Their Positioning Respective to In Silico Tools. (June 2019) Authors: Docci, Luca; Parrott, Neil; Krähenbühl, Stephan; Fowler, Stephen Journal: SLAS discovery Issue: Volume 24:Number 5(2019) Page Start: 523 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
4. Characterization of the Ontogeny of Hepatic UDP‐Glucuronosyltransferase Enzymes Based on Glucuronidation Activity Measured in Human Liver Microsomes. (10th September 2019) Authors: Badée, Justine; Qiu, Nahong; Collier, Abby C.; Takahashi, Ryan H.; Forrest, William F.; Parrott, Neil; Schmidt, Stephan; Fowler, Stephen Other Names: Burckart Gilbert J. guestEditor.; van den Anker John N. guestEditor. Journal: Journal of clinical pharmacology Issue: Volume 59(2019)Supplement 1 Page Start: S42 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
5. Coexpression of Human Hepatic Uridine Diphosphate Glucuronosyltransferase Proteins: Implications for Ontogenetic Mechanisms and Isoform Coregulation. (26th December 2019) Authors: Liu, Yuejian; Badée, Justine; Takahashi, Ryan H.; Schmidt, Stephan; Parrott, Neil; Fowler, Stephen; Mackenzie, Peter I.; Coughtrie, Michael W. H.; Collier, Abby C. Journal: Journal of clinical pharmacology Issue: Volume 60:Number 6(2020) Page Start: 722 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
6. Current Practices, Gap Analysis, and Proposed Workflows for PBPK Modeling of Cytochrome P450 Induction: An Industry Perspective. Issue 4 (24th December 2021) Authors: Hariparsad, Niresh; Ramsden, Diane; Taskar, Kunal; Badée, Justine; Venkatakrishnan, Karthik; Reddy, Micaela B.; Cabalu, Tamara; Mukherjee, Dwaipayan; Rehmel, Jessica; Bolleddula, Jayaprakasam; Emami Riedmaier, Arian; Prakash, Chandra; Chanteux, Hugues; Mao, Jialin; Umehara, Kenichi; Shah, Ku... Journal: Clinical pharmacology & therapeutics Issue: Volume 112:Issue 4(2022) Page Start: 770 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
7. Development of a physiologically based pharmacokinetic model for mefloquine and its application alongside a clinical effectiveness model to select an optimal dose for prevention of malaria in young Caucasian children. Issue 1 (5th November 2018) Authors: Johnson, Trevor N.; Cleary, Yumi; Parrott, Neil; Reigner, Bruno; Smith, James R.; Toovey, Stephen Journal: British journal of clinical pharmacology Issue: Volume 85:Issue 1(2019) Page Start: 100 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
8. Effect of Food and Esomeprazole on the Pharmacokinetics of Alectinib, a Highly Selective ALK Inhibitor, in Healthy Subjects. Issue 4 (28th September 2016) Authors: Morcos, Peter N.; Guerini, Elena; Parrott, Neil; Dall, Georgina; Blotner, Steven; Bogman, Katrijn; Sturm, Carolina; Balas, Bogdana; Martin‐Facklam, Meret; Phipps, Alex Journal: Clinical pharmacology in drug development Issue: Volume 6:Issue 4(2017) Page Start: 388 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
9. Effect of Hepatic Impairment on the Pharmacokinetics of Alectinib. (27th July 2018) Authors: Morcos, Peter N.; Cleary, Yumi; Sturm‐Pellanda, Carolina; Guerini, Elena; Abt, Markus; Donzelli, Massimiliano; Vazvaei, Faye; Balas, Bogdana; Parrott, Neil; Yu, Li Journal: Journal of clinical pharmacology Issue: Volume 58:Number 12(2018) Page Start: 1618 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
10. Effect of the Wetting Agent Sodium Lauryl Sulfate on the Pharmacokinetics of Alectinib: Results From a Bioequivalence Study in Healthy Subjects. Issue 3 (3rd October 2016) Authors: Morcos, Peter N.; Parrott, Neil; Banken, Ludger; Timpe, Carsten; Lindenberg, Marc; Guerini, Elena; Dall, Georgina; Bogman, Katrijn; Sturm, Carolina; Zeaiter, Ali; Martin‐Facklam, Meret; Phipps, Alex Journal: Clinical pharmacology in drug development Issue: Volume 6:Issue 3(2017) Page Start: 266 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗