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4. Discovery of attenuation effect of orexin 1 receptor to aversion of nalfurafine: Synthesis and evaluation of D-nor-nalfurafine derivatives and analyses of the three active conformations of nalfurafine. Issue 17 (1st September 2020)

6. Essential structure of orexin 1 receptor antagonist YNT-707, Part I: Role of the 4, 5-epoxy ring for binding with orexin 1 receptor. Issue 17 (1st September 2017)

7. Essential structure of orexin 1 receptor antagonist YNT-707, Part II: Drastic effect of the 14-hydroxy group on the orexin 1 receptor antagonistic activity. Issue 4 (15th February 2018)

8. Essential structure of orexin 1 receptor antagonist YNT-707, part III: Role of the 14-hydroxy and the 3-methoxy groups in antagonistic activity toward the orexin 1 receptor in YNT-707 derivatives lacking the 4, 5-epoxy ring. Issue 8 (15th April 2019)

9. Essential structure of orexin 1 receptor antagonist YNT-707, Part IV: The role of D-ring in 4, 5-epoxymorphinan on the orexin 1 receptor antagonistic activity. Issue 18 (15th September 2019)

10. Essential structure of orexin 1 receptor antagonist YNT-707, part V: Structure-activity relationship study of the substituents on the 17-amino group. Issue 3 (1st February 2020)