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You searched for: Author/Creator Morgentin, Rémy

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1. A metal-catalyzed enyne-cyclization step for the synthesis of bi- and tricyclic scaffolds amenable to molecular library production. Issue 29 (30th June 2016)

2. Discovery of 1-(4-(5-(5-amino-6-(5-tert-butyl-1, 3, 4-oxadiazol-2-yl)pyrazin-2-yl)-1-ethyl-1, 2, 4-triazol-3-yl)piperidin-1-yl)-3-hydroxypropan-1-one (AZD8835): A potent and selective inhibitor of PI3Kα and PI3Kδ for the treatment of cancers. Issue 22 (15th November 2015)

3. Discovery of a series of 8-(1-phenylpyrrolidin-2-yl)-6-carboxamide-2-morpholino-4H-chromen-4-one as PI3Kβ/δ inhibitors for the treatment of PTEN-deficient tumours. Issue 9 (1st May 2017)

4. Discovery of a series of 8-(2, 3-dihydro-1, 4-benzoxazin-4-ylmethyl)-2-morpholino-4-oxo-chromene-6-carboxamides as PI3Kβ/δ inhibitors for the treatment of PTEN-deficient tumours. Issue 9 (1st May 2016)

5. Petasis/Diels–Alder/Cyclization Cascade Reactions for the Generation of Scaffolds with Multiple Stereogenic Centers and Orthogonal Handles for Library Production. Issue 36 (15th June 2018)

6. Petasis/Diels–Alder/Cyclization Cascade Reactions for the Generation of Scaffolds with Multiple Stereogenic Centers and Orthogonal Handles for Library Production. Issue 46 (13th December 2018)

7. Realisation of small molecule libraries based on frameworks distantly related to natural products. Issue 17 (12th April 2018)

8. Squaramides as novel class I and IIB histone deacetylase inhibitors for topical treatment of cutaneous t-cell lymphoma. Issue 17 (15th September 2018)

9. Synthesis of 1, 4, 5 trisubstituted γ-lactams via a 3-component cascade reaction. Issue 11 (1st June 2015)