1. Benzydamine N-oxygenation as an index for flavin-containing monooxygenase activity and benzydamine N-demethylation by cytochrome P450 enzymes in liver microsomes from rats, dogs, monkeys, and humans. Issue 1 (February 2015) Authors: Taniguchi-Takizawa, Tomomi; Shimizu, Makiko; Kume, Toshiyuki; Yamazaki, Hiroshi Journal: Drug metabolism and pharmacokinetics Issue: Volume 30:Issue 1(2015) Page Start: 64 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Different substrate elimination rates of model drugs pH-dependently mediated by flavin-containing monooxygenases and cytochromes P450 in human liver microsomes. (October 2021) Authors: Taniguchi-Takizawa, Tomomi; Kato, Nozomu; Shimizu, Makiko; Kume, Toshiyuki; Yamazaki, Hiroshi Journal: Drug metabolism and pharmacokinetics Issue: Volume 40(2021) Page Start: Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. Estimation of changes in serum creatinine and creatinine clearance caused by renal transporter inhibition in healthy subjects. Issue 4 (August 2019) Authors: Nakada, Tomohisa; Kudo, Toshiyuki; Kume, Toshiyuki; Kusuhara, Hiroyuki; Ito, Kiyomi Journal: Drug metabolism and pharmacokinetics Issue: Volume 34:Issue 4(2019) Page Start: 233 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
4. Fluorescent indicator displacement assay for the discovery of UGGAA repeat-targeted small molecules. Issue 34 (6th April 2023) Authors: Shibata, Tomonori; Matsumoto, Yasumasa; Iihara, Akiko; Yamada, Kazunori; Ochiai, Hiroshi; Saito, Ryo; Kusaka, Shinichi; Kume, Toshiyuki Journal: Chemical communications Issue: Volume 59:Issue 34(2023) Page Start: 5071 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
5. Functional characterization for polymorphic organic anion transporting polypeptides (OATP/SLCO1B1, 1B3, 2B1) of monkeys recombinantly expressed with various OATP probes. (10th February 2019) Authors: Takahashi, Tsuyoshi; Uno, Yasuhiro; Yamazaki, Hiroshi; Kume, Toshiyuki Journal: Biopharmaceutics & drug disposition Issue: Volume 40:Number 2(2019:Mar.) Page Start: 62 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
6. Key determinants of the circulatory exposure of organic anions: differences in hepatic uptake between multidrug resistance-associated protein 2 (Mrp2)-deficient rats and wild-type rats. (June 2015) Authors: Kosaka, Keigo; Watanabe, Tomoko; Susukida, Takeshi; Aoki, Shigeki; Sekine, Shuichi; Kume, Toshiyuki; Ito, Kousei Journal: Xenobiotica Issue: Volume 45:Number 6(2015:Jun.) Page Start: 556 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
7. Metabolism and disposition of the dipeptidyl peptidase IV inhibitor teneligliptin in humans. (March 2014) Authors: Nakamaru, Yoshinobu; Hayashi, Yoshiharu; Ikegawa, Ruriko; Kinoshita, Shuji; Madera, Begonya Perez; Gunput, Dave; Kawaguchi, Atsuhiro; Davies, Martin; Mair, Stuart; Yamazaki, Hiroshi; Kume, Toshiyuki; Suzuki, Masayuki Journal: Xenobiotica Issue: Volume 44:Number 3(2014:Mar.) Page Start: 242 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
8. Precise prediction of activators for the human constitutive androstane receptor using structure-based three-dimensional quantitative structure–activity relationship methods. Issue 3 (June 2017) Authors: Kato, Harutoshi; Yamaotsu, Noriyuki; Iwazaki, Norihiko; Okamura, Shigeaki; Kume, Toshiyuki; Hirono, Shuichi Journal: Drug metabolism and pharmacokinetics Issue: Volume 32:Issue 3(2017) Page Start: 179 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
9. Pre‐incubation with cyclosporine A potentiates its inhibitory effects on pitavastatin uptake mediated by recombinantly expressed cynomolgus monkey hepatic organic anion transporting polypeptide. (14th October 2016) Authors: Takahashi, Tsuyoshi; Ohtsuka, Tatsuyuki; Uno, Yasuhiro; Utoh, Masahiro; Yamazaki, Hiroshi; Kume, Toshiyuki Journal: Biopharmaceutics & drug disposition Issue: Volume 37:Number 8(2016:Nov.) Page Start: 479 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
10. Quantitative analysis of elevation of serum creatinine via renal transporter inhibition by trimethoprim in healthy subjects using physiologically-based pharmacokinetic model. Issue 1 (February 2018) Authors: Nakada, Tomohisa; Kudo, Toshiyuki; Kume, Toshiyuki; Kusuhara, Hiroyuki; Ito, Kiyomi Journal: Drug metabolism and pharmacokinetics Issue: Volume 33:Issue 1(2018) Page Start: 103 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗