1. A Model‐Based Workflow to Benchmark the Clinical Cholestasis Risk of Drugs. Issue 5 (28th September 2021) Authors: Baier, Vanessa; Clayton, Olivia; Nudischer, Ramona; Cordes, Henrik; Schneider, Annika R. P.; Thiel, Christoph; Wittenberger, Timo; Moritz, Wolfgang; Blank, Lars M.; Neumann, Ulf P.; Trautwein, Christian; Kelm, Jens; Schrooders, Yannick; Caiment, Florian; Gmuender, Hans; Roth, Adrian; Castell, Jos... Journal: Clinical pharmacology & therapeutics Issue: Volume 110:Issue 5(2021) Page Start: 1293 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. A Systematic Evaluation of the Use of Physiologically Based Pharmacokinetic Modeling for Cross‐Species Extrapolation. Issue 1 (12th November 2014) Authors: Thiel, Christoph; Schneckener, Sebastian; Krauss, Markus; Ghallab, Ahmed; Hofmann, Ute; Kanacher, Tobias; Zellmer, Sebastian; Gebhardt, Rolf; Hengstler, Jan G.; Kuepfer, Lars Journal: Journal of pharmaceutical sciences Issue: Volume 104:Issue 1(2015:Jan.) Page Start: 191 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. Algorithmic surveillance of ICU patients with acute respiratory distress syndrome (ASIC): protocol for a multicentre stepped-wedge cluster randomised quality improvement strategy. Issue 4 (8th April 2021) Authors: Marx, Gernot; Bickenbach, Johannes; Fritsch, Sebastian Johannes; Kunze, Julian Benedict; Maassen, Oliver; Deffge, Saskia; Kistermann, Jennifer; Haferkamp, Silke; Lutz, Irina; Voellm, Nora Kristiana; Lowitsch, Volker; Polzin, Richard; Sharafutdinov, Konstantin; Mayer, Hannah; Kuepfer, Lars; Burgha... Journal: BMJ open Issue: Volume 11:Issue 4(2021) Page Start: Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
4. Bringing in vitro analysis closer to in vivo: Studying doxorubicin toxicity and associated mechanisms in 3D human microtissues with PBPK-based dose modelling. (15th September 2018) Authors: Verheijen, Marcha; Schrooders, Yannick; Gmuender, Hans; Nudischer, Ramona; Clayton, Olivia; Hynes, James; Niederer, Steven; Cordes, Henrik; Kuepfer, Lars; Kleinjans, Jos; Caiment, Florian Journal: Toxicology letters Issue: Volume 294(2018) Page Start: 184 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
5. Data‐driven personalization of a physiologically based pharmacokinetic model for caffeine: A systematic assessment. (26th June 2021) Authors: Fendt, Rebekka; Hofmann, Ute; Schneider, Annika R. P.; Schaeffeler, Elke; Burghaus, Rolf; Yilmaz, Ali; Blank, Lars Mathias; Kerb, Reinhold; Lippert, Jörg; Schlender, Jan‐Frederik; Schwab, Matthias; Kuepfer, Lars Journal: CPT: pharmacometrics & systems pharmacology Issue: Volume 10:Number 7(2021) Page Start: 782 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
6. Early prediction of decompensation (EPOD) score: Non‐invasive determination of cirrhosis decompensation risk. (3rd February 2022) Authors: Schneider, Annika R. P.; Schneider, Carolin V.; Schneider, Kai Markus; Baier, Vanessa; Schaper, Steffen; Diedrich, Christian; Coboeken, Katrin; Mayer, Hannah; Gu, Wenyi; Trebicka, Jonel; Blank, Lars M.; Burghaus, Rolf; Lippert, Joerg; Rader, Daniel J.; Thaiss, Christoph A.; Schlender, Jan‐Frederi... Journal: Liver international Issue: Volume 42:Number 3(2022) Page Start: 640 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
7. Integration of genome-scale metabolic networks into whole-body PBPK models shows phenotype-specific cases of drug-induced metabolic perturbation. (December 2018) Authors: Cordes, Henrik; Thiel, Christoph; Baier, Vanessa; Blank, Lars; Kuepfer, Lars Journal: Npj systems biology and applications Issue: Volume 4(2018) Page Start: 1 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
8. Modeling approaches for hepatic spatial heterogeneity in pharmacokinetic simulations. (2016) Authors: Schwen, Lars Ole; Kuepfer, Lars; Preusser, Tobias Journal: Drug discovery today Issue: Volume 22(2016) Page Start: 35 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
9. Quantitative systems pharmacology of the eye: Tools and data for ocular QSP. (27th January 2023) Authors: Kuepfer, Lars; Fuellen, Georg; Stahnke, Thomas Journal: CPT: pharmacometrics & systems pharmacology Issue: Volume 12:Number 3(2023) Page Start: 288 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
10. Towards knowledge-driven cross-species extrapolation. (2016) Authors: Thiel, Christoph; Hofmann, Ute; Ghallab, Ahmed; Gebhardt, Rolf; Hengstler, Jan G.; Kuepfer, Lars Journal: Drug discovery today Issue: Volume 22(2016) Page Start: 21 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗