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Author/Creator Isaacs, Adrian M

1. C9orf72 ALS/FTD dipeptide repeat protein levels are reduced by small molecules that inhibit PKA or enhance protein degradation. (18th November 2021)

Authors:
Licata, Nausicaa V; Cristofani, Riccardo; Salomonsson, Sally; Wilson, Katherine M; Kempthorne, Liam; Vaizoglu, Deniz; D'Agostino, Vito G; Pollini, Daniele; Loffredo, Rosa; Pancher, Michael; Adami, Valentina; Bellosta, Paola; Ratti, Antonia; Viero, Gabriella; Quattrone, Alessandro; Isaacs, Adrian ...
Journal:
EMBO journal
Issue:
Volume 41:Number 1(2022)
Page Start:
n/a
Record Type:
Journal Article
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2. C9orf72 expansions in frontotemporal dementia and amyotrophic lateral sclerosis. Issue 3 (March 2015)

Authors:
Rohrer, Jonathan D; Isaacs, Adrian M; Mizlienska, Sarah; Mead, Simon; Lashley, Tammaryn; Wray, Selina; Sidle, Katie; Fratta, Pietro; Orrell, Richard W; Hardy, John; Holton, Janice; Revesz, Tamas; Rossor, Martin N; Warren, Jason D
Journal:
Lancet neurology
Issue:
Volume 14:Issue 3(2015:Mar.)
Page Start:
291
Record Type:
Journal Article
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3. C9orf72 expansions in frontotemporal dementia and amyotrophic lateral sclerosis. Issue 3 (March 2015)

Authors:
Rohrer, Jonathan D; Isaacs, Adrian M; Mizielinska, Sarah; Mead, Simon; Lashley, Tammaryn; Wray, Selina; Sidle, Katie; Fratta, Pietro; Orrell, Richard W; Hardy, John; Holton, Janice; Revesz, Tamas; Rossor, Martin N; Warren, Jason D
Journal:
Lancet neurology
Issue:
Volume 14:Issue 3(2015:Mar.)
Page Start:
291
Record Type:
Journal Article
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4. Development of a sensitive trial-ready poly(GP) CSF biomarker assay for C9orf72-associated frontotemporal dementia and amyotrophic lateral sclerosis. Issue 7 (4th April 2022)

Authors:
Wilson, Katherine M; Katona, Eszter; Glaria, Idoia; Carcolé, Mireia; Swift, Imogen J; Sogorb-Esteve, Aitana; Heller, Carolin; Bouzigues, Arabella; Heslegrave, Amanda J; Keshavan, Ashvini; Knowles, Kathryn; Patil, Saurabh; Mohapatra, Susovan; Liu, Yuanjing; Goyal, Jaya; Sanchez-Valle, Raquel; Lafo...
Other Names:
author non-byline.; Afonso Sónia author non-byline.; Almeida Maria Rosario author non-byline.; Anderl-Straub Sarah author non-byline.; Andersson Christin author non-byline.; Antonell Anna author non-byline.; Archetti Silvana author non-byline.; Arighi Andrea author non-byline.; Balasa Mircea aut...
Journal:
Journal of neurology, neurosurgery and psychiatry
Issue:
Volume 93:Issue 7(2022)
Page Start:
761
Record Type:
Journal Article
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5. FUS ALS-causative mutations impair FUS autoregulation and splicing factor networks through intron retention. Issue 12 (1st June 2020)

Authors:
Humphrey, Jack; Birsa, Nicol; Milioto, Carmelo; McLaughlin, Martha; Ule, Agnieszka M; Robaldo, David; Eberle, Andrea B; Kräuchi, Rahel; Bentham, Matthew; Brown, Anna-Leigh; Jarvis, Seth; Bodo, Cristian; Garone, Maria G; Devoy, Anny; Soraru, Gianni; Rosa, Alessandro; Bozzoni, Irene; Fisher, E...
Journal:
Nucleic acids research
Issue:
Volume 48:Issue 12(2020)
Page Start:
6889
Record Type:
Journal Article
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7. G‐quadruplex‐binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo. Issue 1 (7th November 2017)

Authors:
Simone, Roberto; Balendra, Rubika; Moens, Thomas G; Preza, Elisavet; Wilson, Katherine M; Heslegrave, Amanda; Woodling, Nathan S; Niccoli, Teresa; Gilbert‐Jaramillo, Javier; Abdelkarim, Samir; Clayton, Emma L; Clarke, Mica; Konrad, Marie‐Therese; Nicoll, Andrew J; Mitchell, Jamie S; Calvo, Andrea...
Journal:
EMBO molecular medicine
Issue:
Volume 10:Issue 1(2018)
Page Start:
22
Record Type:
Journal Article
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8. Mice with endogenous TDP‐43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis. (15th May 2018)

Authors:
Fratta, Pietro; Sivakumar, Prasanth; Humphrey, Jack; Lo, Kitty; Ricketts, Thomas; Oliveira, Hugo; Brito‐Armas, Jose M; Kalmar, Bernadett; Ule, Agnieszka; Yu, Yichao; Birsa, Nicol; Bodo, Cristian; Collins, Toby; Conicella, Alexander E; Mejia Maza, Alan; Marrero‐Gagliardi, Alessandro; Stewart, Mich...
Journal:
EMBO journal
Issue:
Volume 37:Number 11(2018)
Page Start:
n/a
Record Type:
Journal Article
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10. Quantitative Assessment of Eye Phenotypes for Functional Genetic Studies Using Drosophila melanogaster. Issue 5 (1st May 2016)

Authors:
Iyer, Janani; Wang, Qingyu; Le, Thanh; Pizzo, Lucilla; Grönke, Sebastian; Ambegaokar, Surendra S; Imai, Yuzuru; Srivastava, Ashutosh; Troisí, Beatriz Llamusí; Mardon, Graeme; Artero, Ruben; Jackson, George R; Isaacs, Adrian M; Partridge, Linda; Lu, Bingwei; Kumar, Justin P; Girirajan, Santhosh
Journal:
G3
Issue:
Volume 6:Issue 5(2016)
Page Start:
1427
Record Type:
Journal Article
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