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Author/Creator Hutton, Michael

1. Structure guided design of a series of selective pyrrolopyrimidinone MARK inhibitors. Issue 1 (1st January 2017)

Authors:
Katz, Jason D.; Haidle, Andrew; Childers, Kaleen K.; Zabierek, Anna A.; Jewell, James P.; Hou, Yongquan; Altman, Michael D.; Szewczak, Alexander; Chen, Dapeng; Harsch, Andreas; Hayashi, Mansuo; Warren, Lee; Hutton, Michael; Nuthall, Hugh; Su, Hua-Poo; Munshi, Sanjeev; Stanton, Matt G.; Davies, Ia...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 27:Issue 1(2017)
Page Start:
114
Record Type:
Journal Article
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2. MARK inhibitors: Declaring a No-Go decision on a chemical series based on extensive DMPK experimentation. Issue 1 (1st January 2017)

Authors:
Haidle, Andrew M.; Childers, Kaleen K.; Zabierek, Anna A.; Katz, Jason D.; Jewell, James P.; Hou, Yongquan; Altman, Michael D.; Szewczak, Alexander; Chen, Dapeng; Harsch, Andreas; Hayashi, Mansuo; Warren, Lee; Hutton, Michael; Nuthall, Hugh; Stanton, Matt G.; Davies, Ian W.; Munoz, Ben; Northrup,...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 27:Issue 1(2017)
Page Start:
109
Record Type:
Journal Article
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4. P4‐079: In Vivo Two‐Photon Imaging of the Effects of Tauopathy and Amyloidopathy on Synapse Dynamics in the RTG4510 and J20 Transgenic Models, Respectively. (1st July 2016)

Authors:
Jackson, Johanna; Tamagnini, Francesco; Johnson, James; Ahmed, Zeshan; Oliver-Evans, Alice; Meftah, Soraya; Hutton, Michael; Isaac, John; Randall, Andrew; Ashby, Michael; O'Neill, Michael J.
Journal:
Alzheimer's & dementia
Issue:
Volume 12:Supplement 7S(2016)Part 21
Page Start:
P1043
Record Type:
Journal Article
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5. Tau: From research to clinical development. Issue 10 (3rd May 2016)

Authors:
Holtzman, David M.; Carrillo, Maria C.; Hendrix, James A.; Bain, Lisa J.; Catafau, Ana M.; Gault, Laura M.; Goedert, Michel; Mandelkow, Eckhard; Mandelkow, Eva‐Maria; Miller, David S.; Ostrowitzki, Susanne; Polydoro, Manuela; Smith, Sean; Wittmann, Marion; Hutton, Michael
Journal:
Alzheimer's & dementia
Issue:
Volume 12:Issue 10(2016)
Page Start:
1033
Record Type:
Journal Article
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6. P4–047: Characterization of a seed‐competent tau species in a cell‐based model of tauopathy. (1st July 2013)

Authors:
Jackson, Samuel; Landi, Alessia; Cavallini, Annalisa; Befi, Gabriella; Murray, Tracey; Barnham, Luanda; Glover, Sarah; Szekeres, Philip; Goedert, Michel; O'Neill, Michael; Hutton, Michael; Bose, Suchira
Journal:
Alzheimer's & dementia
Issue:
Volume 9:Supplement 4S(2013)Part 18
Page Start:
P719
Record Type:
Journal Article
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8. P3‐049: CHARACTERISATION OF A CO‐CULTURE CELL‐BASED MODEL OF TAU AGGREGATION AND PROPAGATION. (1st July 2014)

Authors:
Cavallini, Annalisa; Jackson, Samuel; Sanchez, Josep Monserrat; Murray, Tracey; Falcon, Benjamin; Isaacs, Adrian; Goedert, Michel; O'Neill, Michael; Hutton, Michael; Bose, Suchira
Journal:
Alzheimer's & dementia
Issue:
Volume 10:Supplement 4S(2014)Part 18
Page Start:
P646
Record Type:
Journal Article
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9. P4‐210: THE DEMENTIA CONSORTIUM: AN INTERNATIONAL PARTNERSHIP MODEL TO ACCELERATE DRUG DISCOVERY. (1st July 2014)

Authors:
Ridley, Simon; Young, Duncan; Bryans, Justin; Dawson, Lee; Takle, Andy; Bowman, David; Hutton, Michael; Hooper, Nigel; Sivyer, Beth; Elsom, Jane; Sancho, Rosa; Karran, Eric
Journal:
Alzheimer's & dementia
Issue:
Volume 10:Supplement 4S(2014)Part 23
Page Start:
P865
Record Type:
Journal Article
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10. P4‐401: Combination Therapy with a Plaque‐Specific Abeta Antibody And A Bace Inhibitor Results in Dramatic Plaque Reduction in a Dose‐Dependent Manner in Aged Pdapp Transgenic Mice. (1st July 2016)

Authors:
Hole, Justin T.; Racke, Margaret M.; Tzaferis, John A.; Liu, Feng; Oluoch, Herold; Ahmed, Zeshan; Fisher, Alice; Anderson, Wesley; Iversent, Philip; Gonzales, Celedon; Yang, Zhixiang; Boggs, Leonard N.; Monk, Scott A.; Mergott, Dustin J.; Yang, Ying YT.; Lu, Jirong; Irizarry, Michael C.; Sims, Jo...
Journal:
Alzheimer's & dementia
Issue:
Volume 12:Supplement 7S(2014)Part 24
Page Start:
P1191
Record Type:
Journal Article
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