1. A8 Large animal models in huntington's disease: conceptual overview: what model to use for what purpose. (13th September 2016) Authors: Howland, David Journal: Journal of neurology, neurosurgery and psychiatry Issue: Volume 87(2016)Supplement 1 Page Start: A3 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. B03 Analysis of a Huntington's disease knock-in mouse model designed to prevent the generation of the exon 1 HTT protein. (12th September 2022) Authors: Papadopulou, Aikaterini-Smaragdi; Landles, Christian; Smith, Edward; Bondulich, Marie; Iqbal, Arzo; Osborne, Georgina F; Howland, David; Neueder, Andreas; Bates, Gillian P Journal: Journal of neurology, neurosurgery and psychiatry Issue: Volume 93(2022)Supplement 1 Page Start: A15 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. B1 HTT CAG knock-in mice with pure and interrupted repeat tracts provide insight into the role of somatic expansion in HD pathogenesis. (13th September 2016) Authors: Wheeler, Vanessa C; Kovalenko, Marina; Giordano, James; Andrew, Marissa; Menalled, Liliana; Alexandrov, Vadim; Thiede, Christina; Weidner, Jenny; Teichmann, Kerstin; Tottey, William; Cumming, Sarah A; Correia, Kevin; Barker, Douglas; Lager, Brenda; Flynn, Geraldine; Fischer, David F; Tillack, Kar... Journal: Journal of neurology, neurosurgery and psychiatry Issue: Volume 87(2016)Supplement 1 Page Start: A9 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
4. B3 Comparison of the effect of a pure CAG repeat and mixed cagcaa repeat on the extent to which the htt gene is aberrantly spliced in knock-in mice. (13th September 2016) Authors: Ali, Nadira S; Osborne, Georgina F; Benjamin, Agnesska C; Sathasivam, Kirupa; Neueder, Andreas; Howland, David; Bates, Gillian P Journal: Journal of neurology, neurosurgery and psychiatry Issue: Volume 87(2016)Supplement 1 Page Start: A10 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
5. B4 Detection of the aberrantly spliced exon 1 – intron 1 htt mRNA in HD patient post mortem brain tissue and fibroblast lines. (13th September 2016) Authors: Bates, Gillian P; Osborne, Georgiana F; Ali, Nadira; Benjamin, Agnesska C; Papadopoulou, Aikaterini S; Howland, David; Tabrizi, Sarah J; Faull, Richard LM; Myers, Richard H; Landles, Christian; Neueder, Andreas Journal: Journal of neurology, neurosurgery and psychiatry Issue: Volume 87(2016)Supplement 1 Page Start: A10 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
6. Development of novel bioassays to detect soluble and aggregated Huntingtin proteins on three technology platforms. Issue 1 (5th January 2021) Authors: Landles, Christian; Milton, Rebecca E; Jean, Alexandre; McLarnon, Stuart; McAteer, Sean J; Taxy, Bridget A; Osborne, Georgina F; Zhang, Chuangchuang; Duan, Wenzhen; Howland, David; Bates, Gillian P Journal: Brain communications Issue: Volume 3:Issue 1(2021) Page Start: Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
7. High resolution time-course mapping of early transcriptomic, molecular and cellular phenotypes in Huntington's disease CAG knock-in mice across multiple genetic backgrounds. (27th February 2017) Authors: Ament, Seth A.; Pearl, Jocelynn R.; Grindeland, Andrea; St. Claire, Jason; Earls, John C.; Kovalenko, Marina; Gillis, Tammy; Mysore, Jayalakshmi; Gusella, James F.; Lee, Jong-Min; Kwak, Seung; Howland, David; Lee, Min Young; Baxter, David; Scherler, Kelsey; Wang, Kai; Geman, Donald; Carroll, Jeff... Journal: Human molecular genetics Issue: Volume 26:Number 5(2017:Mar. 01) Page Start: 913 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
8. Mutations causing Lopes-Maciel-Rodan syndrome are huntingtin hypomorphs. Issue 3 (11th January 2021) Authors: Jung, Roy; Lee, Yejin; Barker, Douglas; Correia, Kevin; Shin, Baehyun; Loupe, Jacob; Collins, Ryan L; Lucente, Diane; Ruliera, Jayla; Gillis, Tammy; Mysore, Jayalakshmi S; Rodan, Lance; Picker, Jonathan; Lee, Jong-Min; Howland, David; Lee, Ramee; Kwak, Seung; MacDonald, Marcy E; Gusella, James F;... Journal: Human molecular genetics Issue: Volume 30:Issue 3/4(2021) Page Start: 135 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
9. Myostatin inhibition prevents skeletal muscle pathophysiology in Huntington's disease mice. Issue 1 (December 2017) Authors: Bondulich, Marie; Jolinon, Nelly; Osborne, Georgina; Smith, Edward; Rattray, Ivan; Neueder, Andreas; Sathasivam, Kirupa; Ahmed, Mhoriam; Ali, Nadira; Benjamin, Agnesska; Chang, Xiaoli; Dick, James; Ellis, Matthew; Franklin, Sophie; Goodwin, Daniel; Inuabasi, Linda; Lazell, Hayley; Lehar, Adam; Ri... Journal: Scientific reports Issue: Volume 7:Issue 1(2017) Page Start: 1 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
10. Phenotype onset in Huntington's disease knock‐in mice is correlated with the incomplete splicing of the mutant huntingtin gene. Issue 12 (7th July 2019) Authors: Franich, Nicholas R.; Hickey, Miriam A.; Zhu, Chunni; Osborne, Georgina F.; Ali, Nadira; Chu, Tiffany; Bove, Nicholas H.; Lemesre, Vincent; Lerner, Renata P.; Zeitlin, Scott O.; Howland, David; Neueder, Andreas; Landles, Christian; Bates, Gillian P.; Chesselet, Marie‐Francoise Other Names: Cepeda Carlos guestEditor.; Colwell Christopher S. guestEditor.; Prager Eric M. guestEditor. Journal: Journal of neuroscience research Issue: Volume 97:Issue 12(2019) Page Start: 1590 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗