Search
Search Constraints
You searched for: Author/Creator Guillouzo, André- Guillouzo, André [remove] 11
- Toxicology -- Periodicals 8
- 615.9 5
- Toxicity testing -- In vitro -- Periodicals 5
- 363.179 3
- 571.65505 2
- Peroxisomal disorders -- Periodicals 2
- Peroxisomes -- Periodicals 2
- 616.362 1
- ABT 1-aminobenzotriazole -- Ac-DEVD-AMC N-acetyl-Asp-Glu-Val-Asp-7-amido-4-methylcoumarin -- AC-IETD-AMC Ac-Ile-Glu-Thr-Asp-7-amino-4-methylcoumarin -- AC-LEHD-AMC Ac-Leu-Glu-His-Asp-7-Amino-4-methylcoumarin -- BSEP bile salt export pump -- CDF 5 (and 6)-carboxy-2′, 7′-dichlorofluorescein (CDF) -- CRP C-reactive protein -- CYP cytochrome P450 -- DCF diclofenac -- DMSO dimethyl sulfoxide -- ER endoplasmic reticulum -- H2-DCFDA 2′, 7′-dichlorodihydrofluorescein -- HO1 heme oxygenase 1 -- IL-8 interleukin-8 -- MnSOD manganese superoxide dismutase -- MRP2 multidrug associated protein 2 -- MTT methylthiazoltetrazolium -- NAC N-acetyl cysteine -- NTCP Na+-dependent taurocholate cotransporting polypeptide -- PBS phosphate buffered saline -- ROS reactive oxygen species -- RT-qPCR real-time quantitative polymerase chain reaction -- TNF-α tumor necrosis factor α 1
- ADR adverse drug reaction -- bcell biliary cell -- BSA bovine serum albumin -- Ccell concentration in cell lysate -- Cmax human therapeutic peak plasma concentration -- Cmed concentration in assay medium -- CV coefficient of variation -- CYP cytochrome P450 -- DME drug metabolising enzyme -- DMEM Dulbecco modified eagle medium -- DMSO dimethyl sulphoxide -- FBS foetal bovine serum -- Fin entry rate flow for one cell -- Fout exit rate flow for one cell -- HMM hepatocyte maintenance medium -- IBU ibuprofen -- ITS insulin transferrin selenium -- k1 rate constant for binding to medium proteins -- k2 rate constant for unbinding from medium proteins -- Km Michaelis–Menten constant -- LOD limit of detection -- LOQ limit of quantification -- MCMC Markov-chain Monte Carlo -- Ncell number of cells in the assay system -- NOAEC no observed adverse effect concentration -- OECD Organisation for Economic Co-operation and Development -- PHH primary human hepatocytes -- PBPK physiologically-based pharmacokinetics -- PRH primary rat hepatocytes -- Qcell total quantity in cell lysate -- Qmed total quantity in assay medium -- Qprot total quantity bound on protein -- SD standard deviation -- SW sandwich -- t1/2 half-life -- TC toxic concentration -- Tmax time to reach Cmax -- Vcell volume of a cell -- Vmax maximal metabolic rate -- Vmed volume of assay medium 1