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You searched for: Author/Creator Guest, R.- Guest, R. [remove] 12
- Toxicology -- Periodicals 12
- 615.9 8
- Toxicity testing -- In vitro -- Periodicals 8
- 363.179 4
- CON4EI -- Ocular irritation -- Reference chemicals -- Draize rabbit eye test -- UN GHS categories 2
- BAC benzalkonium chloride -- Cat 1 UN GHS classification for chemicals causing irreversible effects on the eye/serious damage to the eye -- Cat 2 UN GHS classification for chemicals causing reversible effects on the eye/eye irritation, sub-categorized in 2A (irritant to eyes, eye effects are not fully reversible within 7 days of observation) and 2B (mild irritant to eyes, eye effects fully reversible within 7 days of observation) -- CO corneal opacity -- Conj conjunctival redness (CR) and/or conjunctival chemosis (CC) -- CO pers. D21 CO persistence on day 21 -- CON4EI CONsortium for in vitro Eye Irritation testing strategy -- CP contact period -- CP1% 60-min CP with a 1% w/v concentration of the chemical -- CP10% 60-min CP with a 10% w/v concentration of the chemical -- CP3.5% 60-min CP with a 3.5% w/v concentration of the chemical -- DRD Draize eye test Reference Database -- FNR false negative rate -- FPR false positive rate -- IR iritis -- MP mucus production -- MP CP1% amount of mucus produced during CP1% -- MP CP10% amount of mucus produced during CP10% -- MP CP3.5% amount of mucus produced during CP3.5% -- NC negative control -- OECD Organization for Economic Co-operation and Development -- PC positive control -- pers persistence -- SMI Slug Mucosal Irritation -- TG Test Guideline -- UN GHS United Nations Globally Harmonized System of Classification and Labelling of Chemicals 1
- BCOP Bovine Corneal Opacity and Permeability -- BCOP LLBO Bovine Corneal Opacity and Permeability Laser Light based Opacitometer -- CAS RN Chemical Abstracts Service Registry Number -- Cat1 UN GHS classification for chemicals causing irreversible effects on the eye/serious damage to the eye -- Cat2 UN GHS classification for chemicals causing reversible effects on the eye/eye irritation, sub-categorised in 2A (irritant to eyes, eye effects are not fully reversible within 7 days of observation) and 2B (mild irritant to eyes, eye effects fully reversible within 7 days of observation) -- CO Corneal Opacity -- CON4EI CONsortium for in vitro Eye Irritation testing strategy -- EIT Eye Irritation Test -- EITL Eye Irritation Testing of Liquid/Viscous chemicals -- EITS Eye Irritation Testing of Solid chemicals -- EU CLP EU Classification, Labelling and Packaging regulation -- EURL ECVAM European Union Reference Laboratory for Alternatives to Animal Testing -- HCE Human Corneal Epithelium -- NC Negative control -- No Cat Chemicals not classified for serious eye damage/eye irritation under GHS/EU CLP -- No Pred No prediction can be made -- MTT 3-(4, 5-Dimethylthiazole-2-yl)-2, 5-diphenyltetrazolium bromide -- OD Optical density -- OECD Organisation for Economic Co-operation and Development -- PC Positive control -- PBS Phosphate-buffered saline -- pers Persistence -- RhCE Reconstructed human Cornea-like Epithelium -- SkinEthic™ HCE EIT SkinEthic™ Human Corneal Epithelium Eye Irritation Test -- SOP Standard operating procedure -- SMI Slug mucosal irritation -- TG Test Guideline -- UN GHS United Nations Globally Harmonized System of Classification and Labelling of Chemicals -- VITO Flemish Institute for Technological Research 1
- BCOP bovine corneal opacity and permeability -- BCOP LLBO bovine corneal opacity and permeability laser light-based opacitometer -- CAS RN chemical abstracts service registry number -- Cat 1 UN GHS classification for chemicals causing irreversible effects on the eye/serious damage to the eye -- Cat 2 UN GHS classification for chemicals causing reversible effects on the eye/eye irritation, sub-catagorised in 2A (irritant to eyes, eye effects are not fully reversible within 7 days of observation) and 2B (mild irritant to eyes, eye effects fully reversible within 7 days of observation) -- CO corneal opacity -- CON4EI CONsortium for in vitro eye irritation testing strategy -- DRD Draize eye test reference database -- EIT Eye irritation test -- EU CLP EU classification, labeling and packaging regulation -- EpiOcular ET-50 EpiOcular time to toxicity test -- EpiOcular EIT EpiOcular eye irritation test -- EURL ECVAM European Union reference laboratory for alternatives to animal testing -- GD guidance document -- HCE Human Corneal Epithelium -- ICE Isolated Chicken Eye -- NC negative control -- No Cat chemicals not classified for serious eye damage/eye irritation under GHS/EU CLP -- No Pred no prediction can be made -- OECD Organisation for Economic Co-operation and Development -- pers persistence -- RhCE Reconstructed human Cornea-like Epithelium -- SkinEthic™ HCE EIT SkinEthic™ Human Corneal Epithelium Eye irritation Test -- SMI Slug Mucosal Irritation -- STE Short Time Exposure -- TG Test Guideline -- UN GHS United Nations Globally Harmonized System of Classification and Labelling of Chemicals -- WNT Working Group of the National Coordinators 1
- BfR Bundesinstitut für Risikobewertung, Federal Institute for risk assessment, Germany -- Cat1 UN GHS classification for chemicals causing irreversible effects on the eye/serious damage to the eye -- Cat2 UN GHS classification for chemicals causing reversible effects on the eye/eye irritation, sub-categorised in 2A (irritant to eyes, eye effects are not fully reversible within 7 days of observation) and 2B (mild irritant to eyes, eye effects fully reversible within 7 days of observation) -- CON4EI CONsortium for in vitro Eye Irritation testing strategy -- EU European Union -- EU CLP EU Classification, Labelling and Packaging regulation (EC) No 1272/2008 -- FN false negative -- FP false positive -- JRC European Commission - Joint Research Centre, Varese, Italy -- No Cat chemicals not classified for serious eye damage/eye irritation under GHS/EU CLP -- OECD Organisation for Economic Co-operation and Development -- QSAR quantitative structure-activity relationship -- SAR structure-activity relationship -- REACH registration, evaluation, authorisation and restriction of chemicals -- Regulation (EC) no 1907/2006 -- SMILES simplified molecular input line entry specification -- TN true negative -- TP true positive -- UN GHS United Nations Globally Harmonized System of Classification and Labelling of Chemicals -- VITO Flemish Institute for Technological Research 1
- CON4EI -- Eye irritation/serious eye damage -- Slug Mucosal Irritation (SMI) test method 1