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Author/Creator Guagnano, Vito

1. Discovery of a novel class of highly potent inhibitors of the p53–MDM2 interaction by structure-based design starting from a conformational argument. Issue 19 (1st October 2016)

Authors:
Furet, Pascal; Masuya, Keiichi; Kallen, Joerg; Stachyra-Valat, Thérèse; Ruetz, Stephan; Guagnano, Vito; Holzer, Philipp; Mah, Robert; Stutz, Stefan; Vaupel, Andrea; Chène, Patrick; Jeay, Sébastien; Schlapbach, Achim
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 26:Issue 19(2016)
Page Start:
4837
Record Type:
Journal Article
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2. Front Cover: Structural States of Hdm2 and HdmX: X‐ray Elucidation of Adaptations and Binding Interactions for Different Chemical Compound Classes (ChemMedChem 14/2019). (17th July 2019)

Authors:
Kallen, Joerg; Izaac, Aude; Chau, Suzanne; Wirth, Emmanuelle; Schoepfer, Joseph; Mah, Robert; Schlapbach, Achim; Stutz, Stefan; Vaupel, Andrea; Guagnano, Vito; Masuya, Keiichi; Stachyra, Therese‐Marie; Salem, Bahaa; Chene, Patrick; Gessier, Francois; Holzer, Philipp; Furet, Pascal
Journal:
ChemMedChem
Issue:
Volume 14:Number 14(2019)
Page Start:
1304
Record Type:
Journal Article
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3. Front Cover: The First Class of Small Molecules Potently Disrupting the YAP‐TEAD Interaction by Direct Competition (ChemMedChem 19/2022). (6th October 2022)

Authors:
Furet, Pascal; Bordas, Vincent; Le Douget, Mickaël; Salem, Bahaa; Mesrouze, Yannick; Imbach‐Weese, Patricia; Sellner, Holger; Voegtle, Markus; Soldermann, Nicolas; Chapeau, Emilie; Wartmann, Markus; Scheufler, Clemens; Fernandez, Cesar; Kallen, Joerg; Guagnano, Vito; Chène, Patrick; Schmelzle, To...
Journal:
ChemMedChem
Issue:
Volume 17:Number 19(2022)
Page Start:
n/a
Record Type:
Journal Article
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4. In vitro and in vivo characterization of a novel, highly potent p53-MDM2 inhibitor. Issue 20 (1st November 2018)

Authors:
Vaupel, Andrea; Holzer, Philipp; Ferretti, Stephane; Guagnano, Vito; Kallen, Joerg; Mah, Robert; Masuya, Keiichi; Ruetz, Stephan; Rynn, Caroline; Schlapbach, Achim; Stachyra, Thérèse; Stutz, Stefan; Todorov, Milen; Jeay, Sébastien; Furet, Pascal
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 28:Issue 20(2018)
Page Start:
3404
Record Type:
Journal Article
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5. Increasing metabolic stability via the deuterium kinetic isotope effect: An example from a proline-amide-urea aminothiazole series of phosphatidylinositol-3 kinase alpha inhibitors. Issue 19 (1st October 2016)

Authors:
Fairhurst, Robin A.; Caravatti, Giorgio; Guagnano, Vito; Aichholz, Reiner; Blanz, Joachim; Blasco, Francesca; Wipfli, Peter; Fritsch, Christine; Maira, Sauveur-Michel; Schnell, Christian; Seiler, Frank H.
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 26:Issue 19(2016)
Page Start:
4729
Record Type:
Journal Article
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6. Optimisation of a 5-[3-phenyl-(2-cyclic-ether)-methyl-ether]-4-aminopyrrolopyrimidine series of IGF-1R inhibitors. Issue 8 (15th April 2016)

Authors:
Fairhurst, Robin A.; Marsilje, Thomas H.; Stutz, Stefan; Boos, Andreas; Niklaus, Michel; Chen, Bei; Jiang, Songchun; Lu, Wenshuo; Furet, Pascal; McCarthy, Clive; Stauffer, Frédéric; Guagnano, Vito; Vaupel, Andrea; Michellys, Pierre-Yves; Schnell, Christian; Jeay, Sébastien
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 26:Issue 8(2016)
Page Start:
2057
Record Type:
Journal Article
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7. Pharmacological inhibition of fibroblast growth factor (FGF) receptor signaling ameliorates FGF23‐mediated hypophosphatemic rickets. (18th March 2013)

Authors:
Wöhrle, Simon; Henninger, Christine; Bonny, Olivier; Thuery, Anne; Beluch, Noemie; Hynes, Nancy E; Guagnano, Vito; Sellers, William R; Hofmann, Francesco; Kneissel, Michaela; Graus Porta, Diana
Journal:
Journal of bone and mineral research
Issue:
Volume 28:Number 4(2013:Apr.)
Page Start:
899
Record Type:
Journal Article
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8. Structural States of Hdm2 and HdmX: X‐ray Elucidation of Adaptations and Binding Interactions for Different Chemical Compound Classes. (27th May 2019)

Authors:
Kallen, Joerg; Izaac, Aude; Chau, Suzanne; Wirth, Emmanuelle; Schoepfer, Joseph; Mah, Robert; Schlapbach, Achim; Stutz, Stefan; Vaupel, Andrea; Guagnano, Vito; Masuya, Keiichi; Stachyra, Therese‐Marie; Salem, Bahaa; Chene, Patrick; Gessier, Francois; Holzer, Philipp; Furet, Pascal
Journal:
ChemMedChem
Issue:
Volume 14:Number 14(2019)
Page Start:
1305
Record Type:
Journal Article
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Available online (eLD content is only available in our Reading Rooms) ↗

9. The First Class of Small Molecules Potently Disrupting the YAP‐TEAD Interaction by Direct Competition. (2nd September 2022)

Authors:
Furet, Pascal; Bordas, Vincent; Le Douget, Mickaël; Salem, Bahaa; Mesrouze, Yannick; Imbach‐Weese, Patricia; Sellner, Holger; Voegtle, Markus; Soldermann, Nicolas; Chapeau, Emilie; Wartmann, Markus; Scheufler, Clemens; Fernandez, Cesar; Kallen, Joerg; Guagnano, Vito; Chène, Patrick; Schmelzle, To...
Journal:
ChemMedChem
Issue:
Volume 17:Number 19(2022)
Page Start:
n/a
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗