1. A dysregulated interleukin-18–interferon-γ–CXCL9 axis impacts treatment response to canakinumab in systemic juvenile idiopathic arthritis. (10th February 2021) Authors: Hinze, Tanja; Kessel, Christoph; Hinze, Claas H; Seibert, Julia; Gram, Hermann; Foell, Dirk Journal: Rheumatology Issue: Volume 60:Number 11(2021) Page Start: 5165 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Diffuse traumatic axonal injury in mice induces complex behavioural alterations that are normalized by neutralization of interleukin‐1β. (11th March 2016) Authors: Ekmark‐Lewén, Sara; Flygt, Johanna; Fridgeirsdottir, Gudrun A.; Kiwanuka, Olivia; Hånell, Anders; Meyerson, Bengt J.; Mir, Anis K.; Gram, Hermann; Lewén, Anders; Clausen, Fredrik; Hillered, Lars; Marklund, Niklas Editors: Chan, Ying‐Shing Journal: European journal of neuroscience Issue: Volume 43:Number 8(2016:Apr.) Page Start: 1016 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. Early changes in gene expression and inflammatory proteins in systemic juvenile idiopathic arthritis patients on canakinumab therapy. Issue 1 (December 2017) Authors: Brachat, Arndt; Grom, Alexei; Wulffraat, Nico; Brunner, Hermine; Quartier, Pierre; Brik, Riva; McCann, Liza; Ozdogan, Huri; Rutkowska-Sak, Lidia; Schneider, Rayfel; Gerloni, Valeria; Harel, Liora; Terreri, Maria; Houghton, Kristin; Joos, Rik; Kingsbury, Daniel; Lopez-Benitez, Jorge; Bek, Stephan;... Journal: Arthritis research & therapy Issue: Volume 19:Issue 1(2017) Page Start: 1 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
4. Interleukin-1β suppression dampens inflammatory leucocyte production and uptake in atherosclerosis . Issue 13 (28th October 2021) Authors: Hettwer, Jan; Hinterdobler, Julia; Miritsch, Benedikt; Deutsch, Marcus-André; Li, Xinghai; Mauersberger, Carina; Moggio, Aldo; Braster, Quinte; Gram, Hermann; Robertson, Avril A B; Cooper, Matthew A; Groß, Olaf; Krane, Markus; Weber, Christian; Koenig, Wolfgang; Soehnlein, Oliver; Adamstein, Nich... Editors: Mallat, Ziad Journal: Cardiovascular research Issue: Volume 118:Issue 13(2022) Page Start: 2778 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
5. Mechanistic Insights to the Differential Effects of Interleukin-1 Isoforms on Experimental Atherosclerosis. (June 2018) Authors: Vromman, Amelie; Ruvkun, Victoria; Shvartz, Eugenia; Wojtkiewicz, Gregory; Masson, Gustavo Santos; Tesmenitsky, Yevgenia; Gram, Hermann; Folco, Eduardo; Swirski, Filip; Nahrendorf, Matthias; Sukhova, Galina; Libby, Peter Journal: Atherosclerosis Issue: Volume 32(2018) Page Start: 105 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
6. Preclinical characterization and clinical development of ILARIS® (canakinumab) for the treatment of autoinflammatory diseases. (June 2016) Authors: Gram, Hermann Journal: Current opinion in chemical biology Issue: Volume 32(2016) Page Start: 1 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
7. Reducing Vascular Calcification by Anti-IL-1β Monoclonal Antibody in a Mouse Model of Familial Hypercholesterolemia. (February 2016) Authors: Awan, Zuhier; Denis, Maxime; Roubtsova, Anna; Essalmani, Rachid; Marcinkiewicz, Jadwiga; Awan, Amani; Gram, Hermann; Seidah, Nabil G.; Genest, Jacques Journal: Angiology Issue: Volume 67:Number 2(2016) Page Start: 157 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
8. Stage-dependent differential effects of interleukin-1 isoforms on experimental atherosclerosis. (30th January 2019) Authors: Vromman, Amélie; Ruvkun, Victoria; Shvartz, Eugenia; Wojtkiewicz, Gregory; Santos Masson, Gustavo; Tesmenitsky, Yevgenia; Folco, Eduardo; Gram, Hermann; Nahrendorf, Matthias; Swirski, Filip K; Sukhova, Galina K; Libby, Peter Journal: European heart journal Issue: Volume 40:Number 30(2019) Page Start: 2482 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
9. The long and winding road in pharmaceutical development of canakinumab from rare genetic autoinflammatory syndromes to myocardial infarction and cancer. (April 2020) Authors: Gram, Hermann Journal: Pharmacological research Issue: Volume 154(2020) Page Start: Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
10. Therapeutic Administration of a Monoclonal Anti-Il-1β Antibody Protects Against Experimental Melioidosis. Issue 5 (November 2016) Authors: Weehuizen, Tassili A. F.; Lankelma, Jacqueline M.; De Jong, Hanna K.; De Boer, Onno J.; Roelofs, Joris J. T. H.; Day, Nicholas P.; Gram, Hermann; De Vos, Alex F.; Wiersinga, W. Joost Journal: Shock Issue: Volume 46:Issue 5(2016:Nov.) Page Start: Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗