1. A campaign targeting a conserved Hsp70 binding site uncovers how subcellular localization is linked to distinct biological activities. Issue 8 (18th August 2022) Authors: Shao, Hao; Taguwa, Shuhei; Gilbert, Luke; Shkedi, Arielle; Sannino, Sara; Guerriero, Christopher J.; Gale-Day, Zachary J.; Young, Zapporah T.; Brodsky, Jeffrey L.; Weissman, Jonathan; Gestwicki, Jason E.; Frydman, Judith Journal: Cell chemical biology Issue: Volume 29:Issue 8(2022) Page Start: 1303 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Allosteric HSP70 inhibitors perturb mitochondrial proteostasis and overcome proteasome inhibitor resistance in multiple myeloma. Issue 8 (18th August 2022) Authors: Ferguson, Ian D.; Lin, Yu-Hsiu T.; Lam, Christine; Shao, Hao; Tharp, Kevin M.; Hale, Martina; Kasap, Corynn; Mariano, Margarette C.; Kishishita, Audrey; Patiño Escobar, Bonell; Mandal, Kamal; Steri, Veronica; Wang, Donghui; Phojanakong, Paul; Tuomivaara, Sami T.; Hann, Byron; Driessen, Christoph;... Journal: Cell chemical biology Issue: Volume 29:Issue 8(2022) Page Start: 1288 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. Allosteric inhibition of HSP70 in collaboration with STUB1 augments enzalutamide efficacy in antiandrogen resistant prostate tumor and patient-derived models. (March 2023) Authors: Xu, Pengfei; Yang, Joy C.; Ning, Shu; Chen, Bo; Nip, Christopher; Wei, Qiang; Liu, Liangren; Johnson, Oleta T.; Gao, Allen C.; Gestwicki, Jason E.; Evans, Christopher P.; Liu, Chengfei Journal: Pharmacological research Issue: Volume 189(2023) Page Start: Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
4. BAG3 Is a Modular, Scaffolding Protein that physically Links Heat Shock Protein 70 (Hsp70) to the Small Heat Shock Proteins. Issue 1 (6th January 2017) Authors: Rauch, Jennifer N.; Tse, Eric; Freilich, Rebecca; Mok, Sue-Ann; Makley, Leah N.; Southworth, Daniel R.; Gestwicki, Jason E. Journal: Journal of molecular biology Issue: Volume 429:Issue 1(2017) Page Start: 128 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
5. Caspase inhibition mitigates tau cleavage and neurotoxicity in iPSC‐induced neurons with the V337M MAPT mutation. (1st February 2022) Authors: Theofilas, Panos; Ambrose, Andrew J.; Butler, David; Wang, Chao; Morales, Dulce O.; Petersen, Cathrine; Chin, Brian; Yang, Teddy; Khan, Shireen; Ng, Raymond; Kayed, Rakez; Karch, Celeste M.; Miller, Bruce L.; Gestwicki, Jason E.; Gan, Li; Temple, Sally; Arkin, Michelle R.; Grinberg, Lea T. Journal: Alzheimer's & dementia Issue: Volume 17(2021)Supplement 3 Page Start: n/a Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
6. Caspase inhibition mitigates tau cleavage and neurotoxicity in iPSC‐induced neurons with the V337M MAPT mutation. (December 2021) Authors: Theofilas, Panos; Ambrose, Andrew J.; Butler, David; Wang, Chao; Morales, Dulce O.; Petersen, Cathrine; Chin, Brian; Yang, Teddy; Khan, Shireen; Ng, Raymond; Kayed, Rakez; Karch, Celeste M.; Miller, Bruce L.; Gestwicki, Jason E.; Gan, Li; Temple, Sally; Arkin, Michelle R.; Grinberg, Lea T. Journal: Alzheimer's & dementia Issue: Volume 17(2021)Supplement 3 Page Start: n/a Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
7. Chemical validation of a druggable site on Hsp27/HSPB1 using in silico solvent mapping and biophysical methods. (15th March 2021) Authors: Makley, Leah N.; Johnson, Oleta T.; Ghanakota, Phani; Rauch, Jennifer N.; Osborn, Delaney; Wu, Taia S.; Cierpicki, Tomasz; Carlson, Heather A.; Gestwicki, Jason E. Journal: Bioorganic & medicinal chemistry Issue: Volume 34(2021) Page Start: Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
8. Concise synthesis of spergualin-inspired molecules with broad-spectrum antibiotic activity1. Issue 5 (13th May 2015) Authors: Assimon, Victoria A.; Shao, Hao; Garneau-Tsodikova, Sylvie; Gestwicki, Jason E. Journal: MedChemComm Issue: Volume 6:Issue 5(2015:May) Page Start: 912 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
9. Differential scanning fluorimetry (DSF) screen to identify inhibitors of Hsp60 protein–protein interactions. Issue 22 (27th May 2020) Authors: Shao, Hao; Oltion, Keely; Wu, Taia; Gestwicki, Jason E. Journal: Organic & biomolecular chemistry Issue: Volume 18:Issue 22(2020) Page Start: 4157 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
10. Expanding the Number of 'Druggable' Targets: Non‐Enzymes and Protein–Protein Interactions. (17th December 2012) Authors: Makley, Leah N.; Gestwicki, Jason E. Journal: Chemical biology & drug design Issue: Volume 81:Number 1(2013:Jan.) Page Start: 22 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗