1. 059 Daridorexant: A dual, equipotent, and insurmountable antagonist of both orexin-1 and orexin-2 receptors. (3rd May 2021) Authors: Grandjean, Celia Mueller; Kiry, Manon; Vaillant, Catherine; Nayler, Oliver; Gatfield, John Journal: Sleep Issue: Volume 44(2021)Supplement 2 Page Start: A25 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. ChemInform Abstract: From Bosentan (Tracleer®) to Macitentan (Opsumit®): The Medicinal Chemistry Perspective. Issue 37 (August 2016) Authors: Boss, Christoph; Bolli, Martin H.; Gatfield, John Journal: ChemInform Issue: Volume 47:Issue 37(2016) Page Start: no Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. Cover Picture: Discovery of Highly Potent Dual Orexin Receptor Antagonists via a Scaffold‐Hopping Approach (ChemMedChem 19/2016). (4th October 2016) Authors: Heidmann, Bibia; Gatfield, John; Roch, Catherine; Treiber, Alexander; Tortoioli, Simone; Brotschi, Christine; Williams, Jodi T.; Bolli, Martin H.; Abele, Stefan; Sifferlen, Thierry; Jenck, François; Boss, Christoph Journal: ChemMedChem Issue: Volume 11:Number 19(2016) Page Start: 2097 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
4. Discovery and Characterization of ACT‐335827, an Orally Available, Brain Penetrant Orexin Receptor Type 1 Selective Antagonist. Issue 6 (15th April 2013) Authors: Steiner, Michel A.; Gatfield, John; Brisbare‐Roch, Catherine; Dietrich, Hendrik; Treiber, Alexander; Jenck, Francois; Boss, Christoph Journal: ChemMedChem Issue: Volume 8:Issue 6(2013:Jun.) Page Start: 898 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
5. Discovery and Characterization of ACT‐335827, an Orally Available, Brain Penetrant Orexin Receptor Type 1 Selective Antagonist. Issue 6 (15th April 2013) Authors: Steiner, Michel A.; Gatfield, John; Brisbare‐Roch, Catherine; Dietrich, Hendrik; Treiber, Alexander; Jenck, Francois; Boss, Christoph Journal: ChemMedChem Issue: Volume 8:Issue 6(2013:Jun.) Page Start: 898 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
6. Discovery and optimisation of 1-acyl-2-benzylpyrrolidines as potent dual orexin receptor antagonists1. Issue 6 (10th June 2015) Authors: Williams, Jodi T.; Gatfield, John; Roch, Catherine; Treiber, Alexander; Jenck, Francois; Bolli, Martin H.; Brotschi, Christine; Sifferlen, Thierry; Heidmann, Bibia; Boss, Christoph Journal: MedChemComm Issue: Volume 6:Issue 6(2015:Jun.) Page Start: 1054 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
7. Discovery of Highly Potent Dual Orexin Receptor Antagonists via a Scaffold‐Hopping Approach. (8th July 2016) Authors: Heidmann, Bibia; Gatfield, John; Roch, Catherine; Treiber, Alexander; Tortoioli, Simone; Brotschi, Christine; Williams, Jodi T.; Bolli, Martin H.; Abele, Stefan; Sifferlen, Thierry; Jenck, François; Boss, Christoph Journal: ChemMedChem Issue: Volume 11:Number 19(2016) Page Start: 2132 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
8. Discovery of novel bridged tetrahydronaphthalene derivatives as potent T/L-type calcium channel blockers. Issue 18 (15th September 2015) Authors: Renneberg, Dorte; Hubler, Francis; Rey, Markus; Hess, Patrick; Delahaye, Stephane; Gatfield, John; Iglarz, Marc; Hilpert, Kurt Journal: Bioorganic & medicinal chemistry letters Issue: Volume 25:Issue 18(2015) Page Start: 3941 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
9. Discovery of novel bridged tetrahydronaphthalene derivatives as potent T/L-type calcium channel blockers. Issue 18 (15th September 2015) Authors: Renneberg, Dorte; Hubler, Francis; Rey, Markus; Hess, Patrick; Delahaye, Stephane; Gatfield, John; Iglarz, Marc; Hilpert, Kurt Journal: Bioorganic & medicinal chemistry letters Issue: Volume 25:Issue 18(2015) Page Start: 3941 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
10. Evaluation of tert‐Butyl Isosteres: Case Studies of Physicochemical and Pharmacokinetic Properties, Efficacies, and Activities. Issue 3 (28th January 2015) Authors: Westphal, Matthias V.; Wolfstädter, Bernd T.; Plancher, Jean‐Marc; Gatfield, John; Carreira, Erick M. Journal: ChemMedChem Issue: Volume 10:Issue 3(2015:Mar.) Page Start: 461 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗